Results 131 to 140 of about 85,261 (235)

Hemidesmosome Mutations Contribute to the Onset and Severity of Acquired Autoimmune Bullous Diseases

MedComm, Volume 7, Issue 3, March 2026.
This study examined hemidesmosome assembly‐related genes in pemphigoid diseases, revealing variants linked to disease onset and severity. Functional analyses, including Caenorhabditis elegans models, Ker‐CT transcriptomics, human proteomics, etc., demonstrated that ITGA6 mutations destabilize hemidesmosomes, disrupt dermal–epidermal adhesion, and ...
Shan Cao, Tianyu Wang, Chen Lv, Shanshan Ma, Gongqi Yu, Qianqian Xia, Tingting Liu, Yueqian Yu, Lele Sun, Xiaoyan Pei, Qing Zhao, Zhenzhen Wang, Chuan Wang, Yongxia Liu, Shengli Chen, Jianwen Wang, Guizhi Zhou, Hong Liu, Yonghu Sun, Furen Zhang   +19 more
wiley   +1 more source

Protected and productive: How greenhouses should deliver UK food security

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 626-638, March 2026.
The United Kingdom produces less than 20% of its fruit and ~50% of its vegetables, leaving it highly import dependent and vulnerable to supply chain disruptions. Our study maps 2085 ha of existing greenhouses, over 70% more than 40 years old, and identifies where modern infrastructure could expand production.
Sven Batke, Nathan Thomas, Nathalie Key, Phil Morley   +3 more
wiley   +1 more source

Population Pharmacokinetic Analysis of Vixarelimab in Healthy Volunteers and Patients With Chronic Pruritic Conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Vixarelimab is a first‐in‐class fully human monoclonal antibody targeting oncostatin M (OSM) receptor beta (OSMRβ). It has been evaluated in Phase 1 and 2 studies in healthy volunteers and patients with chronic pruritic conditions and demonstrated anti‐pruritic efficacy in a Phase 2 study in prurigo nodularis, but detailed pharmacokinetic ...
Fei Tang, Steve Dang, Audrey Arjomandi, Lin Pan, Joy Hsu, Smita Kshirsagar, Nastya Kassir   +6 more
wiley   +1 more source

Hypercapnia as a Key Mechanism in the Development of Pulmonary Hypertension in Malignant Pertussis: A Case Report

Respirology Case Reports, Volume 14, Issue 3, March 2026.
Despite intensive care advances, malignant pertussis (MP) remains highly lethal. Our case suggests that hypercapnia‐induced pulmonary vasoconstriction may play a reversible role in MP pathophysiology. Thus, targeting hypercapnia control could represent a promising therapeutic approach in managing this severe complication.
Juan Ignacio Muñoz‐Bonet, Francisco José Sebastián‐Cuevas, Eva María Flor‐Macián, María del Carmen Ortega‐Sánchez, Andrés Rodríguez‐Sacristán, Juan Brines   +5 more
wiley   +1 more source

Updated Spatial Population Projections for the EU and the UK Under the Shared Socioeconomic Pathways Provide New Insights for Climate Impact Assessments

Earth's Future, Volume 14, Issue 3, March 2026.
Abstract Population development is expected to be one of the main drivers of exposure to climate hazards in the future. However, projecting population development is hindered by large uncertainties in how our socioeconomic future may evolve. The common framework of the Shared Socioeconomic Pathways (SSP) was developed to describe different pathways of ...
Hedda Bonatz, Theodore Nikoletopoulos, Athanasios T. Vafeidis   +2 more
wiley   +1 more source

Significant Influence of Lateral Carbon Fluxes on Regional U.S. Carbon Budgets

Global Biogeochemical Cycles, Volume 40, Issue 3, March 2026.
Abstract Observations of atmospheric carbon dioxide (CO2) are expected to play a critical role in monitoring, reporting, and verification designed to track progress toward the reduction goals of greenhouse gas emissions. In this study, we construct a comprehensive regional carbon budget for seven National Climate Assessment regions of the contiguous ...
B. Byrne, J. Liu, G. M. Domke, S. M. Ogle, G. D. Ferreira, Y. M. Bar‐On, H. Nesser, E. Bilir, A. A. Bloom, D. J. Hayes, B. Poulter, K. W. Bowman, K. J. Davis   +12 more
wiley   +1 more source

Assessing the Effectiveness of Nature‐Based Solutions and Building‐Level Flood Risk Reduction Measures: An Open‐Source Coupled Model

Water Resources Research, Volume 62, Issue 3, March 2026.
Abstract Floods are expected to increase in frequency and severity due to climate change. Recent floods have shown that many catchments worldwide are vulnerable to floods, highlighting the need for additional adaptation measures. This study extends the Geographical, Environmental, and Behavioral (GEB) model by coupling it to a hydrodynamic and a flood ...
Veerle C. Bril, Jens de Bruijn, Hans de Moel, Tarun Sadana, Tim Busker, W. J. Wouter Botzen, Jeroen C. J. H. Aerts   +6 more
wiley   +1 more source

Oncostatin M (OSM) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

OSM PoC 10 Automated Deployment of an IP Telephony Service on UAVs using OSM

, 2020
PoC Key Takeaways - The PoC demonstrates the practical feasibility of automating the deployment of telecommunication services over resource-constrained devices, particularly UAVs. - OSM is intended to support the orchestration of network services over the resource-constrained UAVs.
Nogales, Borja, Vidal, Iván, Sanchez-Aguero, Victor, Valera, Francisco, Gonzalez, Luis. F, Azcorra, Arturo   +5 more
openaire   +1 more source

A Transcriptomic Analysis of Cancer‐Stromal Interactome in Lung Cancer Xenograft Models

Cancer Science, Volume 117, Issue 3, Page 841-851, March 2026.
We conducted a comprehensive analysis of the lung cancer interactome to identify key ligand–receptor pairs involved in the aggressiveness of lung adenocarcinoma. Tumor necrosis factor superfamily member 12 and its receptor tumor necrosis factor receptor superfamily member 12A signaling axis may be potential candidates for therapeutic intervention for ...
Yuriko Takayama‐Isagawa, Daisuke Komura, Takayuki Isagawa, Yusuke Amano, Atsushi Kihara, Tamaki Miura, Taichiro Yoshimoto, Hiroyoshi Tsubochi, Kazutaka Fujita, Koichi Hagiwara, Makoto Maemondo, Tetsuo Ushiku, Shumpei Ishikawa, Noriyoshi Fukushima, Kentaro Inamura, Daisuke Matsubara, Toshiro Niki   +16 more
wiley   +1 more source