Results 131 to 140 of about 86,111 (239)

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Interleukin‐6 and Oncostatin M Levels in Patients With Type 1 Diabetes and Its Relationship With Glycemic Indices

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
In children with type 1 diabetes, serum oncostatin M is significantly elevated and strongly predicts poor glycemic control, while IL‐6 is associated with diabetic ketoacidosis. OSM demonstrates high diagnostic accuracy, suggesting its potential as a sensitive biomarker for early detection and monitoring of paediatric T1DM.
Mona Nourbakhsh, Farzaneh Rouhani, Maryam Razzaghy‐Azar, Mitra Nourbakhsh, Vahid Saeedi, Mahdokht Mehramiz, Davoud Amirkashani, Arash Mohazzab, Taraneh Rezaee   +8 more
wiley   +1 more source

Cognitive Dysfunction Is Associated With an Underestimation of Respiratory Function in ALS

Muscle &Nerve, Volume 73, Issue 5, Page 882-886, May 2026.
ABSTRACT Introduction/Aims The association between low forced vital capacity (FVC) and cognitive impairment in ALS is ambiguous; it could be due to respiratory dysfunction and/or poor effort from cognitive deficits. We used the objective, non‐volitional phrenic nerve motor response amplitude (PAmp) to clarify how cognitive status affects the ...
Horácio de Jesus, Inês Alves, Diana Lopes, Sara Simão, Ana Catarina Leitão, Ana Catarina Pronto‐Laborinho, Vasco Conceição, Miguel Oliveira Santos, Mamede de Carvalho   +8 more
wiley   +1 more source

Myocardial toxicity in two dogs with natural exposure to ractopamine

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract Two dogs that lived in a farm setting were presented to the Texas A&M University Veterinary Medical Teaching Hospital's Emergency Service exhibiting muscle tremors and ventricular arrhythmias following ingestion of ractopamine, a ß‐2 agonist feed‐additive used in beef cattle, pigs and turkeys intended for slaughter to increase muscle mass. The
Sophie Tippit, Igor Yankin, Molly Wart, Sonya Wesselowski   +3 more
wiley   +1 more source

Cryo‐EM reveals ArnA contamination during purification of a ciliary protein complex

Acta Crystallographica Section D, Volume 82, Issue 5, Page 404-410, May 2026.
ArnA contamination was independently observed during the purification of a soluble, low‐yield protein complex, leading to an unintended 3.23 Å resolution cryo‐EM structure. This work broadens recent findings and highlights ArnA as a recurrent His‐tag‐associated contaminant in Escherichia coli purification workflows.Endogenous Escherichia coli proteins ...
Xuguang Jiang, Masahide Kikkawa
wiley   +1 more source

Critical role of the mast cell/tryptase/PAR2 axis in anastrozole‐induced pain

British Journal of Pharmacology, Volume 183, Issue 9, Page 2009-2027, May 2026.
Abstract Background and Purpose Anastrozole, an aromatase inhibitor, is used to treat postmenopausal women with hormone receptor‐positive breast cancer, but also induces musculoskeletal pain and can lead to therapeutic regimen suspension. Aromatase inhibitors promote the release of pro‐inflammatory substances from sensitised nerve fibres, which might ...
Maria Fernanda Pessano Fialho, Raquel Tonello, Evelyne Silva Brum, Gabriela Becker, Nigel W. Bunnett, Sara Marchesan Oliveira   +5 more
wiley   +1 more source

Advancing IBD Management: A Literature Review on the Role of Non‐Invasive Blood‐Based Biomarkers in Predicting and Assessing Pharmacodynamic Response to Treatment

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein, Li Xi, Rathi D. Ryan, Zhan (Harold) Ye, Nessy Tania, Yamato Sano, Joshua Varghese, Diogo Branquinho, Anna Sapone   +8 more
wiley   +1 more source

A unified deep learning framework integrating OpenStreetMap for multi-domain urban planning tasks. [PDF]

Sci Rep
Chen Y, Afandi WS, Gura D, Kosenok Y.
europepmc   +1 more source