Results 71 to 80 of about 85,261 (235)

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

OpenStreetMap e la prima conferenza OSMit

GEOmedia, 2009
OpenStreetMap and the first OSMit conference This month’s article features a brief presentation of the OpenStreetMap project, initiated by a single user in 2004 with the aim of creating a free map of the world, editable following wiki-like rules, and ...
Luca Dellucchi, Niccolò Rigacci, Paolo Cavallini   +2 more
doaj  

UNCERTAINTIES OF COMPLETENESS MEASURES IN OPENSTREETMAP – A CASE STUDY FOR BUILDINGS IN A MEDIUM-SIZED GERMAN CITY [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The completeness of buildings in OpenStreetMap (OSM) is estimated for a medium-sized German city and its surroundings by comparing the OSM data with data from an official building cadastre.
T. Törnros, H. Dorn, S. Hahmann, A. Zipf   +3 more
doaj   +1 more source

Phase diagram of orbital-selective Mott transitions at finite temperatures

, 2005
Mott transitions in the two-orbital Hubbard model with different bandwidths are investigated at finite temperatures. By means of the self-energy functional approach, we discuss the stability of the intermediate phase with one orbital localized and the ...
Anisimov V. I., Bünemann J., Bünemann J., Fang Z., Georges A., Han J. E., Hasegawa H., Held K., Imada M., Imai Y., Kim C.-I., Klejnberg A., Kobayashi Y., Koga A., Koga A., Koga A., Koga A., Koga A., Kotliar G., Kotliar G., Liebsch A., Liebsch A., Liebsch A., Luttinger J. M., Momoi T., Nakatsuji S., Nakatsuji S., Ono Y., Oudovenko V. S., Potthoff M., Potthoff M., Potthoff M., Pruschke T., Rozenberg M. J., Sakai S., Sigrist M., Sreedhar K., Tokura Y., Tomio Y., Zhang Z.   +39 more
core   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

TGM2 Aggravates Acute Pancreatitis by Impairing Macrophage Efferocytosis Through Inhibition of the STAT6–GAS6 Axis

Advanced Science, EarlyView.
This study shows TGM2 is upregulated in AP, impairing macrophage efferocytosis by inhibiting the STAT6–GAS6 axis. The lactoferrin‐modified, ROS‐responsive LF‐LNP@si‐TGM2 targets pancreatic macrophages, silences TGM2, restores the axis, and alleviates AP.
Xuxu Liu, Zhiwei Du, Liyi Wang, Zhihong Xie, Ziang Meng, Yi Zheng, Heming Wang, Yuanhang He, Dongbo Xue   +8 more
wiley   +1 more source

Quantitative analysis of oncostatin M levels in chronic periodontitis patients

Journal of International Clinical Dental Research Organization, 2020
Background: Oncostatin M (OSM) is the cytokine from the family of interleukin-6. Inflammation, tissue turnover, healing, and repair alter the levels of OSM.
Farooque Khan, Surekha Rathod, Abhay Kolte, Madhur Gupta, Suresh Chari, Noopur Gonde   +5 more
doaj   +1 more source

Osm století Chilandaru

Lidé města, 1999
Výstava fotografických reprodukcí Mirkovićových kopií ikon ze srbského kláštera Chilandaru byla připravena velvylanectvím Svazové republiky Jugoslávie u příležitosti 800. výročí založení této srbské svatyně na Svaté Hoře v Řecku. Výstavu autorsky připravil autor kopií Chranislav Mirković, výtvarnou podobu jí dal Jan Duspěva.
openaire   +1 more source

Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity

Advanced NanoBiomed Research, EarlyView.
Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu, Jing Chen, Ji Zhu, Lixin Ru, Dongxiao Zhang   +4 more
wiley   +1 more source