Background Fungi biosynthesize a wide range of chemically diverse secondary metabolites during processes of competition with other micro- and macro-organisms, symbiosis, parasitism, or pathogenesis.
Alessia Staropoli +5 more
doaj +3 more sources
Revolutionizing microbial treasure troves: innovative strategies for natural products discovery [PDF]
Microorganisms represent Earth's most abundant biological resource, producing metabolites of immense value across medicine, agriculture, and industry. Conventional cultivation and screening techniques, however, suffer from inefficiency and fail to meet ...
Yu-Jie Li, Ming-Hua Qiu, Xing-Rong Peng
doaj +2 more sources
New acorane-sesequiterpenes and anti-retinoblastoma constituents from the marine algicolous fungus Trichoderma harzianum NTU2180 guided by molecular networking strategy [PDF]
Background Trichoderma species, known as biocontrol agents against plant diseases, contain diverse compounds, especially terpenoids, with various bioactivities.
Andrea Gu +6 more
doaj +2 more sources
Discovery of Secondary Metabolites from the Sponge-Derived Fungus Aspergillus templicola [PDF]
Combining biosynthetic gene cluster analysis with the OSMAC strategy, fractionation of the fermentation extract of Aspergillus templicola from the sponge Agelas sp. led to the isolation of four novel cytochalasins, colachalasins J–M (1–4), a novel cyclic
Kai Li +5 more
doaj +2 more sources
Antifungal Volatile Organic Compounds from Talaromyces purpureogenus CEF642N: Insights from One Strain Many Compounds (OSMAC) Strategy for Controlling Verticillium dahliae in Cotton [PDF]
Verticillium wilt is a devastating soil-borne disease that significantly impacts cotton production, necessitating the development the effective biofumigants for its control.
Peng Li +7 more
doaj +2 more sources
Study on the anti-vibrio activity of marine fungi Aspergillus sydowii and Rhizopus sp. using OSMAC Approach [PDF]
Shrimp is one of the major aquaculture products in Indonesia. However, shrimp culture faces the peril of Vibriosis, a disease caused by the bacteria genus of Vibrio.
Janarkho, Galank Fad'qul +3 more
core +4 more sources
Polyketide Derivatives from the Mangrove-Derived Fungus Penicillium sp. HDN15-312 [PDF]
Four new polyketides, namely furantides A–B (1–2), talamin E (3) and arugosinacid A (4), and two known polyketides were obtained from the mangrove-derived fungus Penicillium sp. HDN15-312 using the One Strain Many Compounds (OSMAC) strategy.
Fuhao Liu +8 more
doaj +2 more sources
Chemical profiling of fungal metabolites via the OSMAC approach: Novel identification of Brianthein W from an endophytic fungus, Hypomontagnella monticulosa Zg15SU [PDF]
In the previous report, we reported that Hypomontagnella monticulosa originating from the rhizome of Zingiber griffithii was known to produce a marine-derived natural product.
Anisa Lutfia +4 more
doaj +2 more sources
Studies on the Chemical Diversities of Secondary Metabolites Produced by Neosartorya fischeri via the OSMAC Method [PDF]
The One Strain Many Compounds (OSMAC) method was applied to explore the chemical diversities of secondary metabolites produced by Neosartorya fischeri NRRL 181. Four pyripyropenes 1⁻4, eight steroids 5⁻11, and four prenylated indole alkaloids
You-Min Ying +8 more
doaj +3 more sources
Two new caryophyllene-type sesquiterpenes pestalotiopsins U and V (1 and 2) and three known compounds pestalotiopsin B (7), pestaloporinate B (8), and pestalotiopsin C (9) were isolated by the cultivation of the endophytic fungus Pestalotiopsis ...
Xiaoqin Yu +9 more
doaj +3 more sources

