Marine fungi in the spotlight: opportunities and challenges for marine fungal natural product discovery and biotechnology [PDF]
The marine fungal natural products (MaFNaP) Consortium, a scientific network founded in 2014, aims to fuel systematic research on marine fungi and their secondary metabolites.
Tasdemir, Deniz
core +1 more source
Discovery and excavation of lichen bioactive natural products
Lichen natural products are a tremendous source of new bioactive chemical entities for drug discovery. The ability to survive in harsh conditions can be directly correlated with the production of some unique lichen metabolites.
Meirong Ren +5 more
doaj +1 more source
The scarcely investigated myxobacterium Corallococcus coralloides holds a large genome containing many uncharacterized biosynthetic gene clusters (BGCs) that potentially encode the synthesis of entirely new natural products. Despite its promising genomic potential, suitable cultivation conditions have not yet been found to activate the synthesis of new
Jenny Schwarz +4 more
openaire +2 more sources
Endophytic fungi are biodiverse and alternative source of bioactive compounds, due their different abilities of genetic expression and alteration of biosynthetic pathway when submitted to different culture conditions. The metabolic profile of three different crude extracts (A, B and C), obtained from the endophytic fungus Asordaria conoidea, were ...
Arruda, Gabriel Leda de +4 more
openaire +3 more sources
Copper and manganese cations alter secondary metabolism in the fungus Penicillium brasilianum [PDF]
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESThe fungus Penicillium brasilianum LaBioMMi 136 was ...
Amaral, Luciana da Silva +8 more
core +1 more source
Induction of new metabolites from sponge-associated fungus Aspergillus carneus by OSMAC approach
A comparative study on the metabolic profile of the sponge-associated fungus Aspergillus carneus using the OSMAC approach was conducted. The fungal strain was fermented on three different media including solid rice medium with or without sea salt and modified Czapek medium.
Ferhat Can Özkaya +9 more
openaire +3 more sources
The application of an OSMAC (One Strain-Many Compounds) approach on the fungus Pleotrichocladium opacum, isolated from a soil sample collected on the coast of Asturias (Spain), using different culture media, chemical elicitors, and cocultivation techniques resulted in the isolation and identification of nine new compounds (8, 9, 12, 15-18, 20, 21 ...
Víctor Rodríguez Martín-Aragón +5 more
openaire +3 more sources
New Eremophilane-Type Sesquiterpenes from the Marine Sediment-Derived Fungus Emericellopsis maritima BC17 and Their Cytotoxic and Antimicrobial Activities [PDF]
The fungal strain BC17 was isolated from sediments collected in the intertidal zone of the inner Bay of Cadiz and characterized as Emericellopsis maritima.
Aleu Casatejada, Josefina +10 more
core +1 more source
Evolution‐Guided Discovery of Antimycobacterial Triculamin‐Like Lasso Peptides
The hypothesized convergent biosynthesis of triculamin‐like lasso peptides from different biosynthetic gene cluster (BGC) types represented across multiple bacterial phyla. The elucidation of the triculamin non‐canonical BGC and resistance mechanism by heterologous expression in Streptomyces albus and in vitro acetylation with resistance conveying ...
Aske Merrild +3 more
wiley +2 more sources
Toll-like receptor 3 in Epstein-Barr virus-associated nasopharyngeal carcinomas: consistent expression and cytotoxic effects of its synthetic ligand poly(A:U) combined to a Smac-mimetic. [PDF]
published_or_final_versio
Busson, PK +9 more
core +1 more source

