Results 31 to 40 of about 1,517 (182)

Discovery of Novel Phenolic Compounds from <i>Eutypa lata</i> Through OSMAC Approach: Structural Elucidation and Antibiotic Potential. [PDF]

open access: yesInt J Mol Sci
Among grapevine trunk diseases, Eutypa dieback, caused by the fungus Eutypa lata, is one of the most critical ones, due to its widespread infection in vineyards and the lack of effective treatments. This fungus is a vascular pathogen that enters grapevines through pruning wounds.
Cotán A   +6 more
europepmc   +2 more sources

OSMAC Strategy Integrated with Molecular Networking for Accessing Griseofulvin Derivatives from Endophytic Fungi of Moquiniastrum polymorphum (Asteraceae)

open access: yesMolecules, 2021
Three endophytic fungi isolated from Moquiniastrum polymorphum (Less.) G. Sancho (Asteraceae) were cultivated using the one strain many compounds (OSMAC) strategy to evaluate the production of griseofulvin derivatives.
Victor F. Farinella   +5 more
doaj   +1 more source

Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis

open access: yesAngewandte Chemie, Volume 134, Issue 23, June 7, 2022., 2022
Light and glutamic acid induced E. gracilis to produce euglenatides with antifungal and anticancer activity. Euglenatides were also detected in E. sanguinea and E. mutabilis. They resemble the nemamides isolated from C. elegans, inhibited both producing species, and represent uniquely convergent assembly‐line biosynthesis between unicellular organisms ...
Mohammed Aldholmi   +15 more
wiley   +2 more sources

Antibacterial activities of bacteria isolated from the marine sponges Isodictya compressa and Higginsia bidentifera collected from Algoa Bay, South Africa [PDF]

open access: yes, 2017
Due to the rise inmulti-drug resistant pathogens and other diseases, there is renewed interest in marine sponge endosymbionts as a rich source of natural products (NPs).
Davies-Coleman, Michael T.   +4 more
core   +8 more sources

Nocathioamides, Uncovered by a Tunable Metabologenomic Approach, Define a Novel Class of Chimeric Lanthipeptides

open access: yesAngewandte Chemie, Volume 133, Issue 30, Page 16608-16615, July 19, 2021., 2021
Chimeric Lanthipeptides: Employing a tunable metabologenomic approach, nocathioamides A–C were isolated and elucidated. They inaugurate a new RiPP family, characterized by a unique and hyper degree of modifications, including an intramolecular imide bridge.
Hamada Saad   +7 more
wiley   +2 more sources

Expanding the chemical diversity of an endophytic fungus Bulgaria inquinans, an ascomycete associated with mistletoe, through an OSMAC approach. [PDF]

open access: yesRSC Adv, 2019
OSMAC approach on endophyticBulgaria inquinansby addition of a mixture of salts (MgSO4, NaNO3and NaCl) to solid Czapek medium induced the accumulation of new secondary metabolites.
Ariantari NP   +7 more
europepmc   +4 more sources

Chemical profiling of fungal metabolites via the OSMAC approach: Novel identification of Brianthein W from an endophytic fungus, Hypomontagnella monticulosa Zg15SU. [PDF]

open access: yesCurr Res Microb Sci
In the previous report, we reported that Hypomontagnella monticulosa originating from the rhizome of Zingiber griffithii was known to produce a marine-derived natural product. An OSMAC-based approach was designed by modifying the nutritional composition of the growth medium to investigate any possible new metabolites produced by the strain. The culture
Lutfia A   +4 more
europepmc   +4 more sources

Induction of metabolic variability of the endophytic fungus Xylaria sp. by OSMAC approach and experimental design

open access: yesArchives of Microbiology, 2021
This work has as the main focus, to analyze the behavior of physic-chemical variations from the fungus Xylaria sp., through the OSMAC (One Strain, Many Compounds) approach as an efficient way of obtaining new compounds. To perform such inductions and to explore the variability of the metabolic network of this microorganism, a factorial design was ...
Rafael Vieira   +4 more
openaire   +3 more sources

Metabologenomics analysis of Pseudomonas sp. So3.2b, an Antarctic strain with bioactivity against Rhizoctonia solani

open access: yesFrontiers in Microbiology, 2023
IntroductionPhytopathogenic fungi are a considerable concern for agriculture, as they can threaten the productivity of several crops worldwide. Meanwhile, natural microbial products are acknowledged to play an important role in modern agriculture as they
Naydja Moralles Maimone   +6 more
doaj   +1 more source

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