Discovery of Novel Phenolic Compounds from <i>Eutypa lata</i> Through OSMAC Approach: Structural Elucidation and Antibiotic Potential. [PDF]
Among grapevine trunk diseases, Eutypa dieback, caused by the fungus Eutypa lata, is one of the most critical ones, due to its widespread infection in vineyards and the lack of effective treatments. This fungus is a vascular pathogen that enters grapevines through pruning wounds.
Cotán A +6 more
europepmc +2 more sources
Impact of growth conditions on the abundance and diversity of cultivable bacteria recovered from <i>Pheronema carpenteri</i> and investigation of their antimicrobial potential. [PDF]
Conway J +5 more
europepmc +3 more sources
Three endophytic fungi isolated from Moquiniastrum polymorphum (Less.) G. Sancho (Asteraceae) were cultivated using the one strain many compounds (OSMAC) strategy to evaluate the production of griseofulvin derivatives.
Victor F. Farinella +5 more
doaj +1 more source
Light and glutamic acid induced E. gracilis to produce euglenatides with antifungal and anticancer activity. Euglenatides were also detected in E. sanguinea and E. mutabilis. They resemble the nemamides isolated from C. elegans, inhibited both producing species, and represent uniquely convergent assembly‐line biosynthesis between unicellular organisms ...
Mohammed Aldholmi +15 more
wiley +2 more sources
Antibacterial activities of bacteria isolated from the marine sponges Isodictya compressa and Higginsia bidentifera collected from Algoa Bay, South Africa [PDF]
Due to the rise inmulti-drug resistant pathogens and other diseases, there is renewed interest in marine sponge endosymbionts as a rich source of natural products (NPs).
Davies-Coleman, Michael T. +4 more
core +8 more sources
Chimeric Lanthipeptides: Employing a tunable metabologenomic approach, nocathioamides A–C were isolated and elucidated. They inaugurate a new RiPP family, characterized by a unique and hyper degree of modifications, including an intramolecular imide bridge.
Hamada Saad +7 more
wiley +2 more sources
Expanding the chemical diversity of an endophytic fungus Bulgaria inquinans, an ascomycete associated with mistletoe, through an OSMAC approach. [PDF]
OSMAC approach on endophyticBulgaria inquinansby addition of a mixture of salts (MgSO4, NaNO3and NaCl) to solid Czapek medium induced the accumulation of new secondary metabolites.
Ariantari NP +7 more
europepmc +4 more sources
Chemical profiling of fungal metabolites via the OSMAC approach: Novel identification of Brianthein W from an endophytic fungus, Hypomontagnella monticulosa Zg15SU. [PDF]
In the previous report, we reported that Hypomontagnella monticulosa originating from the rhizome of Zingiber griffithii was known to produce a marine-derived natural product. An OSMAC-based approach was designed by modifying the nutritional composition of the growth medium to investigate any possible new metabolites produced by the strain. The culture
Lutfia A +4 more
europepmc +4 more sources
This work has as the main focus, to analyze the behavior of physic-chemical variations from the fungus Xylaria sp., through the OSMAC (One Strain, Many Compounds) approach as an efficient way of obtaining new compounds. To perform such inductions and to explore the variability of the metabolic network of this microorganism, a factorial design was ...
Rafael Vieira +4 more
openaire +3 more sources
IntroductionPhytopathogenic fungi are a considerable concern for agriculture, as they can threaten the productivity of several crops worldwide. Meanwhile, natural microbial products are acknowledged to play an important role in modern agriculture as they
Naydja Moralles Maimone +6 more
doaj +1 more source

