Results 81 to 90 of about 1,517 (182)

Desvendando o potencial bioativo de bactérias marinhas [PDF]

open access: yes, 2021
Besides a primary metabolism, living organisms possess a secondary metabolism which allows for the production of secondary metabolites that, normally, are not fundamental to the organism’s growth and survival.
João, Susana Afonso
core  

Microtiter Plate Cultivation Systems Enable Chemically Diverse Metabolic Footprints During Bacterial Natural Product Discovery

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 8, Page 2021-2036, August 2025.
The utilization of microtiter plate cultivation systems in the discovery of natural products expands the secondary metabolic footprint. Microtiter plate cultivation systems, in particular the 48 well flower plate, facilitate the parallelization of bacterial cultivation and offer a greater degree of comparability to stirred tank bioreactors in ...
Anton Lindig   +2 more
wiley   +1 more source

Recent Advances in the Heterologous Biosynthesis of Natural Products from Streptomyces

open access: yesApplied Sciences, 2021
Streptomyces is a significant source of natural products that are used as therapeutic antibiotics, anticancer and antitumor agents, pesticides, and dyes.
Van Thuy Thi Pham   +5 more
doaj   +1 more source

Product strategies for packaged software : an exploratory analysis of the spreadsheet market [PDF]

open access: yes, 1993
Thesis (M.S.)--Massachusetts Institute of Technology, Sloan School of Management, 1993.Includes bibliographical references (p. 101-113).by Donna D. Mayo and Daniel A.
Mayo, Donna D. (Donna Dorothy)   +1 more
core  

Production of a Novel Tetrahydroxynaphthalene (THN) Derivative from Nocardia sp. CS682 by Metabolic Engineering and Its Bioactivities

open access: yesMolecules, 2019
Nargenicin A1 is major secondary metabolite produced by Nocardia sp. CS682, with an effective antibacterial activity against various Gram-positive bacteria. Most Nocardia spp.
Ravindra Mishra   +6 more
doaj   +1 more source

Use of microwave technology in transdermal drug delivery / Nor Khaizan Anuar [PDF]

open access: yes, 2013
The project focused on the use of microwave in controlling drug release from film matrix and modifying skin barrier for transdermal drug delivery. With reference to controlledrelease application, the effects of microwave on drug release properties of ...
Anuar, Nor Khaizan
core  

ONE STRAIN-MANY COMPOUNDS (OSMAC) METHOD FOR PRODUCTION OF PHENOLIC COMPOUNDS USING Camarops sp., AN ENDOPHYTIC FUNGUS FROM Alibertia macrophylla (Rubiaceae)

open access: yesQuímica Nova
Seven phenolic derivatives including p-hydroxyphenyllactic acid (1), p-hydroxybenzoic acid (2), p-hydroxybenzaldehyde (3), phenyllactic acid (4), n-butyl-3,4-dihydroxybenzoate (5), n-hexyl-3,4-dihydroxybenzoate (6) and n-octyl-3,4-dihydroxybenzoate (7 ...
Juliana R. Gubiani   +5 more
doaj   +1 more source

Integrated genome and metabolome mining unveiled structure and biosynthesis of novel lipopeptides from a deep‐sea Rhodococcus

open access: yesMicrobial Biotechnology, Volume 17, Issue 11, November 2024.
Combining genome mining and mass spectrometry‐based metabolomics disclosed the deep‐sea Rhodococcus sp. I2R as a source of two families of novel lipopeptide biosurfactants with antiproliferative activity against human A375 melanoma cells. Abstract Microbial biosurfactants have garnered significant interest from industry due to their lower toxicity ...
Costanza Ragozzino   +8 more
wiley   +1 more source

OSMAC strategy and LC–MS profiling reveal metabolic diversity and bioactivities of Xylaria thienhirunae SWUF17-44.1

open access: yesAnnals of Microbiology
Background Xylariaceous fungi represent a promising source of secondary metabolites with diverse biological functions. However, their metabolic capacity often remains underestimated under conventional cultivation.
Pitchapa Thongsuwan   +5 more
doaj   +1 more source

Terrosamycins A and B, Bioactive Polyether Ionophores from Streptomyces sp. RKND004 from Prince Edward Island Sediment

open access: yesMarine Drugs, 2019
Terrosamycins A (1) and B (2), two polycyclic polyether natural products, were purified from the fermentation broth of Streptomyces sp. RKND004 isolated from Prince Edward Island sediment.
Amanda Sproule   +6 more
doaj   +1 more source

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