Results 81 to 90 of about 10,230 (254)

Osmium-Promoted σ‑Bond Activation Reactions on Nucleosides [PDF]

, 2020
OsH6(PiPr3)2 has been used to selectively activate C–H, O–H, and C–C sigma bonds in nucleobases and nucleosides, including derivatives of 6-phenylpurine and 4-phenylpyrimidine, leading to cyclometalated mononuclear Os–trihydride complexes, in excellent ...
Mar Gómez-Gallego (1359024), Miguel A. Sierra (1359036), Enrique Oñate (1359039), Miguel A. Esteruelas (1359033), Marta Valencia (1855975), Alba D. Merinero (7861760), Montserrat Oliván (1359027), Carmen Lorenzo-Aparicio (8306433), Beatriz Eguillor (1326744)   +8 more
core   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

New osmium-based reagent for the dihydroxylation of alkenes. [PDF]

, 2006
The cis dihydroxylation of alkenes is most efficiently accomplished by reaction with osmium tetroxide. Recently, the expense and toxicity of osmium tetroxide have led to a number of attempts to harness alternative osmium-based reagents, including ...
Burrows, Jeremy N., Parker, JS, Burrows, JN, Donohoe, Timothy J., Donohoe, Timothy, Harris, RM, Donohoe, TJ, Butterworth, S, Parker, Jeremy S., Cowley, Andrew, Harris, Robert M., Cowley, A, Butterworth, Sam; id_orcid   +12 more
core   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Processing of rare metals containing waste of copper production

Metalurgija, 2018
The article presents the research results processing rare metal-containing waste to produce osmium, rhenium concentrate using technical sulfur. Installed, the optimum leaching conditions sulfided waste.
A. K. Serikbayeva, F. A. Berdikulova, K. K. Mamyrbayeva, Sh. K. Akilbekova   +3 more
doaj  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

MICROINCLUSIONS OF PGM MINERALS IN ANCIENT GOLD PRODUCTS: OCCURRENCE, COMPOSITION, ALTERATION [PDF]

Минералогия, 2015
The PGM microinclusions in ancient gold products from the Urals, Siberia, Azov region and Turkmenistan are compared with similar inclusions from the Middle East artifacts. Microinclusions were found in the archaeological sites, which are located close to
V.V. Zaykov, P.K. Dashkovsky, E.V. Zaykova, V.A. Kotlyarov, A.M. Yuminov, I.A. Blinov   +5 more
doaj  

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Influence of Transition Metals on Animal and Human Health: A Review

Contemporary Agriculture, 2018
Niobium, osmium, scandium, tungsten and vanadium are transition metals naturally occuring in the environment, particularly in the Earth’s crust. Anthropogenic activities, primarily industrial technologies, have precipitated significant alternations in ...
Bilčíková Jana, Fialková Veronika, Kováčiková Eva, Miškeje Michal, Tombarkiewicz Barbara, Kňažická Zuzana   +5 more
doaj   +1 more source