Results 141 to 150 of about 218,046 (303)

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Assessment of Foot Deformities in Patient with Knee Osteoarthritis

Al-Khawarizmi Engineering Journal
Foot morphology evaluation techniques are commonly used to evaluate foot abnormalities. The foot is essential for keeping the biomechanical performance of the lower extremities.
Ruba Musaid, Aseel Ghazwan, Waleed A. Al-Saadan   +2 more
doaj   +1 more source

Quantifying the Tibiofemoral Joint Space Using X-ray Tomosynthesis [PDF]

, 2011
Purpose: Digital x-ray tomosynthesis (DTS) has the potential to provide 3D information about the knee joint in a load-bearing posture, which may improve diagnosis and monitoring of knee osteoarthritis compared with projection radiography, the current ...
Heckel, Beth, Kalinosky, Benjamin, Piacsek, Kelly, Sabol, John M., Schmidt, Taly Gilat   +4 more
core   +1 more source

Correlation Between Synovial Fluid Levels of Matrix Metalloproteinase's (MMP-1, MMP-3, and MMP-9) and TNF-α with the Severity of Osteoarthritis Knee in Rural Indian Population. [PDF]

Indian J Orthop, 2023
Kumar S, Kumar H, Mittal A, Singh PP, Yadav V, Kumar D, Ahmad I, Mishra V.   +7 more
europepmc   +1 more source

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source

Comparison of Functional Outcome of Single Versus Multiple Intra-articular Platelet-Rich Plasma Injection for Early Osteoarthritis Knee. [PDF]

Cureus, 2023
Parmanantham M, Seenappa H, Das S, Shanthappa AH.   +3 more
europepmc   +1 more source

Treatment of large chondral lesions with an autologous minced cartilage technique and synovial flap leads to superior results compared to matrix associated autologous chondrocyte transplantation technique after 24 months: A controlled clinical trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Treating large cartilage lesions in the knee remains a challenge. While matrix‐associated autologous chondrocyte implantation (MACI) is the gold standard for medium to large lesions, the minced cartilage technique has shown promise in smaller defects. Enhancing this technique with biomaterials has been suggested for larger lesions, but
Johanna Mayr, Franziska Warth, Nicola Oehler, Martin Majewski, Christoph Lutter, Fabian Blanke   +5 more
wiley   +1 more source

A Review on Osteoarthritis Knee Management via Contrast Bath Therapy and Physical Therapy. [PDF]

Cureus, 2022
Fokmare PS, Phansopkar P.
europepmc   +1 more source

Preserving scientific integrity in academic publishing: Navigating artificial intelligence, journal policies and the impact factor as a quality indicator

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The integration of artificial intelligence (AI), the rise of mega‐journals, and the manipulation of impact factors present challenges to scientific integrity. These trends threaten the core principles of objectivity, reproducibility, and transparency.
Mahmut Enes Kayaalp, Stefano Zaffagnini, Michael A. Mont, Jon Karlsson, Bruce Reider, Olufemi Ayeni, Thomas Heyse, Henning Madry, Elmar Herbst, Giuseppe Milano, Volker Musahl, Roland Becker, Michael T. Hirschmann   +12 more
wiley   +1 more source

Association of rs763780 variation in interleukin 17F gene with the risk of knee osteoarthritis

Fiyz̤, 2019
Background: The injuries in osteoarthritis are mediated by various cytokines, growth factors, and inflammatory factors and the importance of the interleukin 17 family in this disease is increasingly evident.
Hassan Hassani-Bafrani, Monavareh Ahmadi , Gholam Reza Khosravi, Erfan Khosravi , Mohammad Karimian   +4 more
doaj