Results 101 to 110 of about 693,773 (371)
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko +4 more
wiley +1 more source
Osteoarthritis is characterised by degeneration of joint cartilage. Here the authors show that the RNA-binding protein ZFP36L1 is upregulated in chondrocytes of humans and mice with osteoarthritis, and that its knockdown in mouse joints protects ...
Young-Ok Son +4 more
doaj +1 more source
Purpose We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker +9 more
wiley +1 more source
Aging and Osteoarthritis: An Inevitable Encounter?
Osteoarthritis (OA) is a major health burden of our time. Age is the most prominent risk factor for the development and progression of OA. The mechanistic influence of aging on OA has different facets.
Thomas Hügle +4 more
doaj +1 more source
Evaluation qualitative macroscopique et microscopique du grasset chez un modèle expérimental d'arthrose canine 90 jours après section du ligament croisé crânial [PDF]
La transection du ligament croisé crânial (CCLT) est une méthode couramment admise d'induction expérimentale d'arthrose (OA) au niveau du grasset chez le chien.
Arnault, Fabien +6 more
core
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen +4 more
wiley +1 more source
Objective: Evoked responses following mechanical or thermal stimulation are typically used to assess pain behaviour in murine osteoarthritis (OA). However, there is no consensus on how best to measure spontaneous pain behaviour.
Isabell S. von Loga +5 more
doaj +1 more source
Pulsed electromagnetic energy treatment offers no clinical benefit in reducing the pain of knee osteoarthritis: a systematic review [PDF]
Background The rehabilitation of knee osteoarthritis often includes electrotherapeutic modalities as well as advice and exercise. One commonly used modality is pulsed electromagnetic field therapy (PEMF).
AD Woolf +22 more
core +5 more sources
Knee crepitus and osteoarthritis features in young adults following traumatic knee injury
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One‐year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years)
Jamon L Couch +8 more
wiley +1 more source

