Results 101 to 110 of about 693,773 (371)

Cost‐effectiveness of low dose colchicine prophylaxis when starting allopurinol using the “start‐low go‐slow” approach for gout: evidence from a non‐inferiority randomised double‐blind placebo‐controlled trial.

open access: yesArthritis Care &Research, Accepted Article.
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko   +4 more
wiley   +1 more source

RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family

open access: yesNature Communications, 2019
Osteoarthritis is characterised by degeneration of joint cartilage. Here the authors show that the RNA-binding protein ZFP36L1 is upregulated in chondrocytes of humans and mice with osteoarthritis, and that its knockdown in mouse joints protects ...
Young-Ok Son   +4 more
doaj   +1 more source

Adipokines and Associations with Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Purpose We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker   +9 more
wiley   +1 more source

Aging and Osteoarthritis: An Inevitable Encounter?

open access: yesJournal of Aging Research, 2012
Osteoarthritis (OA) is a major health burden of our time. Age is the most prominent risk factor for the development and progression of OA. The mechanistic influence of aging on OA has different facets.
Thomas Hügle   +4 more
doaj   +1 more source

Evaluation qualitative macroscopique et microscopique du grasset chez un modèle expérimental d'arthrose canine 90 jours après section du ligament croisé crânial [PDF]

open access: yes, 2013
La transection du ligament croisé crânial (CCLT) est une méthode couramment admise d'induction expérimentale d'arthrose (OA) au niveau du grasset chez le chien.
Arnault, Fabien   +6 more
core  

Considerations for Issues of Regression to the Mean and Contextual Effects in Clinical Trials for Pain in Rheumatic Diseases

open access: yesArthritis Care &Research, EarlyView.
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen   +4 more
wiley   +1 more source

Comparison of LABORAS with static incapacitance testing for assessing spontaneous pain behaviour in surgically-induced murine osteoarthritis

open access: yesOsteoarthritis and Cartilage Open, 2020
Objective: Evoked responses following mechanical or thermal stimulation are typically used to assess pain behaviour in murine osteoarthritis (OA). However, there is no consensus on how best to measure spontaneous pain behaviour.
Isabell S. von Loga   +5 more
doaj   +1 more source

Pulsed electromagnetic energy treatment offers no clinical benefit in reducing the pain of knee osteoarthritis: a systematic review [PDF]

open access: yes, 2006
Background The rehabilitation of knee osteoarthritis often includes electrotherapeutic modalities as well as advice and exercise. One commonly used modality is pulsed electromagnetic field therapy (PEMF).
AD Woolf   +22 more
core   +5 more sources

Knee crepitus and osteoarthritis features in young adults following traumatic knee injury

open access: yesArthritis Care &Research, Accepted Article.
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One‐year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years)
Jamon L Couch   +8 more
wiley   +1 more source

Osteoarthritis [PDF]

open access: yesActa Orthopaedica Scandinavica, 1998
Alicia D. Monroe, John B. Murphy
openaire   +4 more sources

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