Results 81 to 90 of about 313,441 (304)

Complicated thromboembolic prophylaxis in the treatment of septic gonitis – case report

Pediatria i Medycyna Rodzinna, 2015
In this paper the case of a patient subjected to orthopaedic treatment with a history of a number of internal comorbidities, cardiac ones in particular, has been reported. Cardiac comorbidities were related to the implantation of a VVI pacemaker.
Adrian Brychcy, Wojciech J. Marczyński, Stanisław Rak   +2 more
doaj   +1 more source

Antinociceptive effects of lacosamide on spinal neuronal and behavioural measures of pain in a rat model of osteoarthritis.

, 2014
Alterations in voltage-gated sodium channel (VGSC) function have been linked to chronic pain and are good targets for analgesics. Lacosamide (LCM) is a novel anticonvulsant that enhances the slow inactivation state of VGSCs. This conformational state can
Wahida Rahman, Anthony H Dickenson, Rahman, W, Dickenson, AH   +3 more
core   +1 more source

A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints [PDF]

, 2009
Background: Osteoarthritis (OA) is the most common joint disease yet its pathophysiology is still poorly understood. It is more prevalent in some lower limb joints than others; in particular the knee is more commonly affected than the ankle.
Beeson, Paul, Hendren, Linda, The University of Northampton   +2 more
core   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source

Efficacy and safety of the long-term oral administration of carprofen in the treatment of osteoarthritis in dogs [PDF]

, 2007
The aim of this study conducted in France was to confirm the efficacy and safety of the oral administration of carprofen (Rimadyl®) at 4 mg/kg once a day during four months in the treatment of clinically chronic osteoarthritis in dogs.
Autefage, André, Gosselin, Jacques
core  

The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis [PDF]

, 2011
Objective To assess if a coding variant in the gene encoding transient receptor potential cation channel, subfamily V, member 1 ( TRPV1 ) is associated with genetic risk of painful knee osteoarthritis (OA). Methods The Ile585Val TRPV1 variant encoded
K. R. Muir, Lories, RJ, C. Cooper, Hart, DJ, D. J. Hart, W. Zhang, Dennison, Elaine M., Arden, Nigel, S. A. Doherty, Chapman, Victoria, Cicuttini, FM, Valdes, Ana M., Doherty, Sally A., Muir, Kenneth R., Vaughn, Frances L., T. D. Spector, Zhang, Weiya, Laslett, LL, Doherty, SA, Arden, N., Lories, Rik J., Chapman, V, Jones, Graeme, A. Soni, Muir, KR, P. Leaverton, V. Chapman, Leaverton, Paul, Spector, T. D., Arden, Nigel K., Jones, G, Cicuttini, Flavia M., Wilde, Gert De, Muir, Kenneth, Doherty, M, G. Jones, Hart, Deborah J., Wheeler, M, R. A. Maciewicz, Leaverton, P, Cooper, Cyrus, N. K. Arden, Valdes, AM, G. De Wilde, Arden, NK, Laslett, Laura L., Vaughn, FL, F. L. Vaughn, De Wilde, G, Zhang, W, A. M. Valdes, Maciewicz, Rose A., Maciewicz, RA, Spector, Tim D., Wheeler, Margaret, Dennison, EM, Spector, TD, M. Doherty, Cooper, C, R. J. Lories, M. Wheeler, Soni, Anushka, E. M. Dennison, F. M. Cicuttini, L. L. Laslett, De Wilde, Gert, Soni, A, Hart, Deborah J.; id_orcid, Doherty, Michael   +68 more
core   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Aging and Osteoarthritis: An Inevitable Encounter?

Journal of Aging Research, 2012
Osteoarthritis (OA) is a major health burden of our time. Age is the most prominent risk factor for the development and progression of OA. The mechanistic influence of aging on OA has different facets.
Thomas Hügle, Jeroen Geurts, Corina Nüesch, Magdalena Müller-Gerbl, Victor Valderrabano   +4 more
doaj   +1 more source

The commercial pig as a model of spontaneously-occurring osteoarthritis [PDF]

, 2019
Background: Preclinical osteoarthritis models where damage occurs spontaneously may better reflect the initiation and development of human osteoarthritis.
Macfadyen, Mhairi A., Tim Parr, Andrew J. Murton, John M. Brameld, Parr, Tim, Murton, Andrew J., Daniel, Zoe, Jones, Simon W., Simon W. Jones, Brameld, John M., Mhairi A. Macfadyen, Sara Kelly, Kelly, Sara, Zoe Daniel   +13 more
core   +1 more source

Resiniferatoxin: Mechanism in Treating Osteoarthritis Pain and Slowing Osteoarthritis Progression, Safety, and Efficacy

, 2023
Resiniferatoxin is a diterpene found in E. resinifera and E. poissonii, and is a more potent functional analog of capsaicin. Resiniferatoxin provides pain relief by binding as an agonist to transient vanilloid receptor 1 (TRPV1), a nociceptive ion ...
David, Liu
core   +1 more source