Results 111 to 120 of about 302,871 (285)
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source
Insights into osteoarthritis development from single-cell RNA sequencing of subchondral bone
Ping Shen, Max Löhning
doaj +1 more source
Production of parathyroid hormone‐related peptide by synovial fibroblasts in human osteoarthritis [PDF]
Tsuyoshi Yoshida +7 more
openalex +1 more source
Efficacy Of Intra-Articular Injection Of Freeze-Dried Platelet Rich Plasma In A Rat Knee Osteoarthritis Model And Characteristics Of Growth Factors Enhanced By Inflammation [PDF]
openalex +1 more source
Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
wiley +1 more source
The Relationship Between Echocardiographic Calcification Score and Grade of Knee Osteoarthritis [PDF]
Ahmet Kıvrak +3 more
openalex +1 more source
Nanozyme‐Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy
A nanozyme–integrated hydrogel (PTC‐MP) exhibiting with mild photothermal effects is constructed, and a “3R” (restrain‐restore‐reinforce) strategy is proposed for diabetic osteoarthritis (DOA) treatment based on advanced glycation end products (AGEs) targeting.
Rui Chen +8 more
wiley +1 more source
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
wiley +1 more source

