Results 131 to 140 of about 508,986 (323)
OBSERVATIONS ON THE LATE RESULTS OF THE McMURRAY OSTEOTOMY FOR OSTEOARTHRITIS OF THE HIP [PDF]
, 1962 Thomas R. King, B. J. Dooley
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Advanced Science, EarlyView.This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang +13 more
wiley +1 more source
A 5-year follow-up of fifty cases of idiopathic osteoarthritis of the hip. [PDF]
, 1969 Monika Seifert +2 more
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Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA
Advanced Science, EarlyView.Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin +9 more
wiley +1 more source
Mefenamic Acid Compared with Indomethacin and Placebo in Osteoarthritis [PDF]
, 1966 Eckhart Buchmann
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Advanced Science, EarlyView.This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan +11 more
wiley +1 more source
The Arrest of Early Primary Osteoarthritis of the Hip by Osteotomy [PDF]
, 1963 K. I. Nissen
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Advanced Science, EarlyView.The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang +5 more
wiley +1 more source
CHONDROITIN SULFATE CONCENTRATION AND PROTEIN-POLYSACCHARIDE COMPOSITION OF ARTICULAR CARTILAGE IN OSTEOARTHRITIS* [PDF]
, 1963 Alfred Jay Bollet +2 more
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Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
Advanced Science, EarlyView.This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li +11 more
wiley +1 more source