Results 141 to 150 of about 708,008 (375)
Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems
Advanced Healthcare Materials, EarlyView.Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei +6 more
wiley +1 more source
Nature Communications, 2017 The pathogenesis of osteoarthritis is unclear. The authors show that estrogen-related receptor gamma is upregulated in cartilage from patients and mouse models, where it drives production of matrix-degrading MMPs in chondrocytes, and that its ...
Young-Ok Son +10 more
doaj +1 more source
The emerging roles of N6-methyladenosine in osteoarthritis [PDF]
, 2022 Hui Liu, Yili Zheng, Xue‐Qiang Wang
openalex +1 more source
Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Advanced Materials, EarlyView.Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source
Evaluation of functional outcome and patient satisfaction after arthroscopic elbow arthrolysis [PDF]
, 2008 Arthroscopic arthrolysis is indicated for stiffness and pain caused by intrinsic stiffness and early arthritis of the elbow joint. Previous studies have demonstrated the benefits in relieving pain and improving motion, but none have reported the ...
Funk, L, Somanchi, BV
core
Cbfβ Is a Novel Modulator against Osteoarthritis by Maintaining Articular Cartilage Homeostasis through TGF-β Signaling [PDF]
, 2023 Xiangguo Che +9 more
openalex +1 more source
Advanced Materials, EarlyView.This review examines hydrogel‐based technologies driven by environmental stimuli and emphasizes their unique contributions to energy conversion. It provides insights into design strategies and recent advancements in functional hydrogels, highlighting opportunities and challenges in this field.
Wanheng Lu +5 more
wiley +1 more source
Engineering Aging: Approaches to Model and Deconstruct Biological Complexity
Advanced Materials, EarlyView.The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar +7 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.A biphasic scaffold comprised of polycaprolactone/laponite and methylsulfonylmethane (MSM)‐loaded polycaprolactone/chitosan is 3D‐printed to form an osteochondral interface. Strong interfacial adhesion between the bone and cartilage layers prevented interfacial separation.
Negin Khoshnood +4 more
wiley +1 more source
Anxiety and depression prevalence and associated factors in patients with knee osteoarthritis
Frontiers in PsychiatryObjectiveWith the evolving spectrum of diseases, psychological conditions such as anxiety and depression have emerged as significant global public health concerns.
Qizhen Feng +4 more
doaj +1 more source