Results 11 to 20 of about 708,008 (375)
Disease-a-Month, 2006 Osteoarthritis is a leading cause of disability and source of societal cost in older adults. With an ageing and increasingly obese population, this syndrome is becoming even more prevalent than in previous decades.
D. Hunter, S. Bierma-Zeinstra
semanticscholar +7 more sources
Nature Reviews Disease Primers, 2016 Osteoarthritis (OA) is the most common joint disorder, is associated with an increasing socioeconomic impact owing to the ageing population and mainly affects the diarthrodial joints. Primary OA results from a combination of risk factors, with increasing age and obesity being the most prominent.
Johanne, Martel-Pelletier +9 more
+8 more sources
Osteoarthritis and Cartilage Open, 2020 Summary: Objective: The aim of the study was to investigate how social housing with high locomotion activity affects experimental osteoarthritis (OA) in rats.
C. Brenneis +5 more
doaj +1 more source
British Journal of Hospital Medicine, 2014 Osteoarthritis is nowadays one of the most frequent chronic diseases and, with the increase in life expectancy, both its prevalence and incidence is expected to rise. This condition is progressive and leads to functional decline and loss in quality of life, with important health care and society costs.
Philip, Courtney, Michael, Doherty
+9 more sources
Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis
International Journal of Molecular Sciences, 2021 Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as a disease of the joint cartilage, osteoarthritis affects all joint tissues equally.
Vilim Molnar +18 more
semanticscholar +1 more source
Diagnostics, 2021 Knee osteoarthritis (OA) is the most common joint disease of the world population. Although considered a disease of old age, OA also affects young individuals and, more specifically among them, those practicing knee-joint-loading sports. Predicting OA at
Johanne Martel-Pelletier +3 more
doaj +1 more source
Subchondral bone microenvironment in osteoarthritis and pain
Bone Research, 2021 Osteoarthritis comprises several joint disorders characterized by articular cartilage degeneration and persistent pain, causing disability and economic burden.
Yan Hu +4 more
semanticscholar +1 more source
Prokineticin 2 is a catabolic regulator of osteoarthritic cartilage destruction in mouse
Arthritis Research & Therapy, 2023 Background Our preliminary study indicates that the multi-functional protein, prokineticin 2 (Prok2), is upregulated in osteoarthritic (OA) chondrocytes as a target of the hypoxia-inducible factor (HIF)-2α.
Jiye Yang +4 more
doaj +1 more source
British medical journal, 2021 Objective To assess the effectiveness and safety of different preparations and doses of non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and paracetamol for knee and hip osteoarthritis pain and physical function to enable effective and safe use ...
B. R. da Costa +17 more
semanticscholar +1 more source
Frontiers in Neurology, 2022 ObjectiveA systematic review of the role of stem cell-derived exosomes in repairing spinal cord injury (SCI) and the existing problems in animal experiments to provide a reference for better animal experiments and clinical studies in the future ...
Cangyu Zhang +14 more
doaj +1 more source