Results 41 to 50 of about 351,906 (249)

Self-reported adult footwear and the risks of lower limb osteoarthritis : the GOAL case control study [PDF]

open access: yes, 2014
Background: Biomechanical factors may play a role in osteoarthritis (OA) development and progression. Previous biomechanical studies have indicated that types of footwear may modulate forces across the knee joint, and high heeled womens’ shoes in ...
Muthuri, Stella   +18 more
core   +2 more sources

Walking time measures for evaluating OA of the knee

open access: yesSouth African Journal of Physiotherapy, 1994
This study assessed the test-retest reliability and the sensitivity of self-paced walking time measurements for evaluating the functional performance of persons with knee osteoarthritis (OA).
R. Marks
doaj   +1 more source

Correction: The role of cumulative physical work load in symptomatic knee osteoarthritis – a case–control study in Germany (Seidler et al. 2008) [PDF]

open access: yes, 2012
: In the original paper (Seidler et al. 2008), there is a mistake in the results of the occupational group analysis. This mistake occurred when the core data set was merged with the occupational group data.
Seidler, Andreas   +7 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Comparison of transdermal and oral anti-inflammatory drugs on immediate post-operative pain control in total knee arthroplasty: a randomized controlled trial

open access: yesArthroplasty
Background Oral nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used as multimodal pain-control medications in total knee arthroplasty (TKA), while topical NSAIDs are commonly used for chronic pain conditions.
Nonn Jaruthien   +6 more
doaj   +1 more source

Osteoarthritis: From Molecular Pathways to Therapeutic Advances [PDF]

open access: yes, 2022
In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely ...

core   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton   +4 more
wiley   +1 more source

Osteoarthritis: musculoskeletal fact sheet [PDF]

open access: yes, 2015
This fact sheet summarises information from the AIHW\u27s online musculoskeletal compendium. Summary Osteoarthritis is a degenerative condition mostly affecting the joints such as hips, knees and ankles.
Australian Institute of Health and Welfare
core  

Antinociceptive effects of lacosamide on spinal neuronal and behavioural measures of pain in a rat model of osteoarthritis. [PDF]

open access: yes, 2014
Alterations in voltage-gated sodium channel (VGSC) function have been linked to chronic pain and are good targets for analgesics. Lacosamide (LCM) is a novel anticonvulsant that enhances the slow inactivation state of VGSCs. This conformational state can
Wahida Rahman   +3 more
core   +1 more source

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