Results 31 to 40 of about 351,906 (249)
Frontiers in Cell and Developmental Biology, 2023 D prostanoid receptor 1 (DP1), a prostaglandin D2 receptor, plays a central role in the modulation of inflammation and cartilage metabolism. We have previously shown that activation of DP1 signaling downregulated catabolic responses in cultured ...
Mehdi Najar +9 more
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Osteoarthritis Management in Primary Care [PDF]
, 2019 Osteoarthritis is one of the most common forms of musculoskeletal conditions seen in general practice. Not only can it cause pain and discomfort, but it can greatly affect the quality of life of patients who live with this conditionJoint pain attributed ...
Cottrell, E, Lambourne, H, Finney, A
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Quantitative sensory testing in painful hand osteoarthritis demonstrates features of peripheral sensitisation. [PDF]
, 2012 Hand osteoarthritis (HOA) is a prevalent condition for which treatments are based on analgesia and physical therapies. Our primary objective was to evaluate pain perception in participants with HOA by assessing the characteristics of nodal involvement ...
Hermansson, M +5 more
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Arthritis Research & Therapy, 2018 Background The weight of recommendation for intra-articular therapies such as hyaluronic acid injections varies from one set of guidelines to another, and they have not yet reached unanimity with respect to the usefulness of intra-articular hyaluronic ...
Jean-Pierre Pelletier +5 more
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Biomedicines, 2022 The hallmark of osteoarthritis (OA), the most prevalent musculoskeletal disease, is the loss of cartilage. By using machine learning (ML), we aimed to assess if baseline knee bone curvature (BC) could predict cartilage volume loss (CVL) at one year, and ...
Hossein Bonakdari +3 more
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Pulsed electromagnetic energy treatment offers no clinical benefit in reducing the pain of knee osteoarthritis: a systematic review [PDF]
, 2006 Background The rehabilitation of knee osteoarthritis often includes electrotherapeutic modalities as well as advice and exercise. One commonly used modality is pulsed electromagnetic field therapy (PEMF).
Michael James Callaghan +12 more
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BMC Musculoskeletal Disorders, 2019 Background Knee osteoarthritis (KOA) is a prevalent form of chronic joint disease associated with functional restrictions and pain. Activity limitations negatively impact social connectedness and psychological well-being, reducing the quality of life ...
Marianna Vitaloni +15 more
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A patients’ view of OA: the Global Osteoarthritis Patient Perception Survey (GOAPPS), a pilot study
BMC Musculoskeletal Disorders, 2020 Background Globally, osteoarthritis (OA) is the third condition associated with disability. There is still poor treatment in OA but science holds the key to finding better treatments and a cure.
Marianna Vitaloni +19 more
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An unusual midfoot injury pattern: Navicular-cuneiform and calcaneal-cuboid fracture-dislocation
Trauma Case Reports, 2022 Fracture-dislocations of the midfoot are relatively rare injuries. We present a case of a 20-year-old man presenting with navicular-cuneiform and calcaneal-cuboid fracture-dislocation of his right foot due to a crush injury during work.
Ali Fares +3 more
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Future directions for the management of pain in osteoarthritis. [PDF]
, 2014 Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA
Kuttapitiya, A, Sofat, N
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