Results 31 to 40 of about 462,319 (292)

Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis: 9-year follow-up data from the Osteoarthritis Initiative

open access: yesArthritis Research & Therapy, 2018
Background The weight of recommendation for intra-articular therapies such as hyaluronic acid injections varies from one set of guidelines to another, and they have not yet reached unanimity with respect to the usefulness of intra-articular hyaluronic ...
Jean-Pierre Pelletier   +5 more
doaj   +1 more source

A Machine Learning Model to Predict Knee Osteoarthritis Cartilage Volume Changes over Time Using Baseline Bone Curvature

open access: yesBiomedicines, 2022
The hallmark of osteoarthritis (OA), the most prevalent musculoskeletal disease, is the loss of cartilage. By using machine learning (ML), we aimed to assess if baseline knee bone curvature (BC) could predict cartilage volume loss (CVL) at one year, and ...
Hossein Bonakdari   +3 more
doaj   +1 more source

The n-acetyl phenylalanine glucosamine derivative attenuates the inflammatory/catabolic environment in a chondrocyte-synoviocyte co-culture system [PDF]

open access: yes, 2019
Osteoarthritis (OA), the most prevalent degenerative joint disease, still lacks a true disease-modifying therapy. The involvement of the NF-κB pathway and its upstream activating kinases in OA pathogenesis has been recognized for many years.
Borzi, R. M.   +7 more
core   +1 more source

Global management of patients with knee osteoarthritis begins with quality of life assessment: a systematic review

open access: yesBMC Musculoskeletal Disorders, 2019
Background Knee osteoarthritis (KOA) is a prevalent form of chronic joint disease associated with functional restrictions and pain. Activity limitations negatively impact social connectedness and psychological well-being, reducing the quality of life ...
Marianna Vitaloni   +15 more
doaj   +1 more source

An unusual midfoot injury pattern: Navicular-cuneiform and calcaneal-cuboid fracture-dislocation

open access: yesTrauma Case Reports, 2022
Fracture-dislocations of the midfoot are relatively rare injuries. We present a case of a 20-year-old man presenting with navicular-cuneiform and calcaneal-cuboid fracture-dislocation of his right foot due to a crush injury during work.
Ali Fares   +3 more
doaj   +1 more source

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. [PDF]

open access: yes, 2015
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With obesity on the rise and the worlds population living longer,
Bhatti, Simi   +3 more
core   +1 more source

Osteoarthritis [PDF]

open access: yesCurrent Opinion in Rheumatology, 2007
Abstract Osteoarthritis (OA) is characterized by degeneration of articular cartilage, limited intraarticular inflammation with synovitis, and changes in peri‐articular and subchondral bone. Multiple factors are involved in the pathogenesis of OA, including mechanical influences, the effects of aging on cartilage matrix composition and
Mary B, Goldring, Steven R, Goldring
openaire   +4 more sources

Walking time measures for evaluating OA of the knee

open access: yesSouth African Journal of Physiotherapy, 1994
This study assessed the test-retest reliability and the sensitivity of self-paced walking time measurements for evaluating the functional performance of persons with knee osteoarthritis (OA).
R. Marks
doaj   +1 more source

A patients’ view of OA: the Global Osteoarthritis Patient Perception Survey (GOAPPS), a pilot study

open access: yesBMC Musculoskeletal Disorders, 2020
Background Globally, osteoarthritis (OA) is the third condition associated with disability. There is still poor treatment in OA but science holds the key to finding better treatments and a cure.
Marianna Vitaloni   +19 more
doaj   +1 more source

変形性膝関節炎患者膝関節液中の細胞外マトリックス成分と可溶性VCAM-1 [PDF]

open access: yes, 1997
It is generally accepted that the number of patients with osteoarthritis (OA) of the knee must increase in the future because of the increase of the aged. The pathogenic mechanisms of OA haven't been elucidated yet, but it is supposed that mediate pannus
Endo, Hiroshi   +5 more
core   +1 more source

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