Disease-a-Month, 2006 Osteoarthritis (OA), the syndrome of joint pain and dysfunction caused by joint degeneration, affects more people than any other joint disease. In most instances joint degeneration develops in the absence of an identifiable cause, but increasing age, excessive joint loading, and joint abnormalities and insults increase the risk of OA. Articular surface
David J, Hunter, David T, Felson
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British Journal of Hospital Medicine, 2014 Osteoarthritis is nowadays one of the most frequent chronic diseases and, with the increase in life expectancy, both its prevalence and incidence is expected to rise. This condition is progressive and leads to functional decline and loss in quality of life, with important health care and society costs.
Philip, Courtney, Michael, Doherty
openaire +6 more sources
Association of malalignment, muscular dysfunction, proprioception, laxity and abnormal joint loading with tibiofemoral knee osteoarthritis - a systematic review and meta-analysis [PDF]
, 2018 Background: To investigate (1) the association of specific biomechanical factors with knee osteoarthritis and knee osteoarthritis development, and (2) the impact of other relevant risk factors on this association.Methods: MEDLINE, EMBASE, CINAHL and ...
Dekker, Joost +6 more
core +5 more sources
Correction: The role of cumulative physical work load in symptomatic knee osteoarthritis – a case–control study in Germany (Seidler et al. 2008) [PDF]
, 2012 : In the original paper (Seidler et al. 2008), there is a mistake in the results of the occupational group analysis. This mistake occurred when the core data set was merged with the occupational group data.
Abolmaali, Nasreddin +3 more
core +1 more source
Memory CD8+ T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals
Frontiers in Immunology, 2019 Memory CD8+ cytotoxic T lymphocytes (CTLs) can protect against viral reinfection. However, the signals driving rapid memory CTL reactivation have remained ill-defined.
Claudia Baumann +10 more
doaj +1 more source
Journal of Translational Medicine, 2020 Background An important task in developing accurate public health intervention evaluation methods based on historical interrupted time series (ITS) records is to determine the exact lag time between pre- and post-intervention.
Hossein Bonakdari +2 more
doaj +1 more source
RMD Open, 2022 Elite athletes are at greater risk of joint injuries linked to the subsequent risk of developing osteoarthritis (OA). Genetic factors such as mitochondrial (mt) DNA haplogroups have been associated with the incidence/progression of OA and athletic ...
Jean-Pierre Pelletier +1 more
doaj +1 more source
The Validity, Reliability, Measurement Error, and Minimum Detectable Change of the 30‐Second Fast‐Paced Walk Test in Persons with Knee Osteoarthritis: A Novel Test of Short‐Distance Walking Ability [PDF]
, 2019 Objective To develop and establish the reliability, validity, measurement error, and minimum detectable change of a novel 30‐second fast‐paced walk test (30SFW) in persons with knee osteoarthritis (OA) that is easy to administer and can quantify walking ...
Folkins, DPT, Erik +3 more
core +2 more sources
Mass spectrometry-based proteomics identify novel serum osteoarthritis biomarkers
Arthritis Research & Therapy, 2022 Background Osteoarthritis (OA) is a slowly developing and debilitating disease, and there are no validated specific biomarkers for its early detection.
Ginette Tardif +9 more
doaj +1 more source
The Complexity of Human Walking: A Knee Osteoarthritis Study [PDF]
, 2014 This study proposes a framework for deconstructing complex walking patterns to create a simple principal component space before checking whether the projection to this space is suitable for identifying changes from the normality.
Duffell, LD +3 more
core +2 more sources