Results 21 to 30 of about 302,871 (285)
RMD Open, 2022 Elite athletes are at greater risk of joint injuries linked to the subsequent risk of developing osteoarthritis (OA). Genetic factors such as mitochondrial (mt) DNA haplogroups have been associated with the incidence/progression of OA and athletic ...
Jean-Pierre Pelletier +1 more
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Scientific Reports, 2021 Sports-related injuries increase healthcare cost burden, and in some instances have harmful long term physical and psychological implications. There is currently a lack of comprehensive data on temporal injury trends across professional North American ...
Garrett S. Bullock +3 more
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Nature Reviews Disease PrimersOsteoarthritis is a heterogeneous whole-joint disease that can cause pain and is a leading cause of disability and premature work loss. The predominant disease risk factors - obesity and joint injury - are well recognized and modifiable. A greater understanding of the complex mechanisms, including inflammatory, metabolic and post-traumatic processes ...
Su’an Tang +10 more
+8 more sources
Frontiers in Cell and Developmental Biology, 2023 D prostanoid receptor 1 (DP1), a prostaglandin D2 receptor, plays a central role in the modulation of inflammation and cartilage metabolism. We have previously shown that activation of DP1 signaling downregulated catabolic responses in cultured ...
Mehdi Najar +9 more
doaj +1 more source
Arthritis Research & Therapy, 2017 Background There is an obvious need to identify biomarkers that could predict patient response to an osteoarthritis (OA) treatment. This post hoc study explored in a 2-year randomized controlled trial in patients with knee OA, the likelihood of some ...
Johanne Martel-Pelletier +6 more
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Arthritis Research & Therapy, 2018 Background The weight of recommendation for intra-articular therapies such as hyaluronic acid injections varies from one set of guidelines to another, and they have not yet reached unanimity with respect to the usefulness of intra-articular hyaluronic ...
Jean-Pierre Pelletier +5 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2019 Background Knee osteoarthritis (KOA) is a prevalent form of chronic joint disease associated with functional restrictions and pain. Activity limitations negatively impact social connectedness and psychological well-being, reducing the quality of life ...
Marianna Vitaloni +15 more
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An unusual midfoot injury pattern: Navicular-cuneiform and calcaneal-cuboid fracture-dislocation
Trauma Case Reports, 2022 Fracture-dislocations of the midfoot are relatively rare injuries. We present a case of a 20-year-old man presenting with navicular-cuneiform and calcaneal-cuboid fracture-dislocation of his right foot due to a crush injury during work.
Ali Fares +3 more
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Current Opinion in Rheumatology, 2007 Abstract Osteoarthritis (OA) is characterized by degeneration of articular cartilage, limited intraarticular inflammation with synovitis, and changes in peri‐articular and subchondral bone. Multiple factors are involved in the pathogenesis of OA, including mechanical influences, the effects of aging on cartilage matrix composition and
Mary B, Goldring, Steven R, Goldring
openaire +4 more sources
Walking time measures for evaluating OA of the knee
South African Journal of Physiotherapy, 1994 This study assessed the test-retest reliability and the sensitivity of self-paced walking time measurements for evaluating the functional performance of persons with knee osteoarthritis (OA).
R. Marks
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