Results 21 to 30 of about 508,986 (323)
Frontiers in Neurology, 2022 ObjectiveA systematic review of the role of stem cell-derived exosomes in repairing spinal cord injury (SCI) and the existing problems in animal experiments to provide a reference for better animal experiments and clinical studies in the future ...
Cangyu Zhang +14 more
doaj +1 more source
Modifications of Gait as Predictors of Natural Osteoarthritis Progression in STR/Ort Mice [PDF]
, 2014 OBJECTIVE: Osteoarthritis (OA) is a common chronic disease for which disease-modifying therapies are not currently available. Studies to seek new targets for slowing the progress of OA rely on mouse models, but these do not allow for longitudinal ...
Bevan, S +10 more
core +8 more sources
In silico targeting of interleukin-6 by natural compounds
Bangladesh Journal of Pharmacology, 2014 Rheumatoid arthritis an autoimmune disorder affecting many tissues and organs, is a challenging prospect in terms of treatment. Our work is looking into finding lead compound of natural origin against IL-6, an important cyto-kine having a profound role ...
Wei Zhou +4 more
doaj +1 more source
Association between osteoarthritis and cardiovascular disease: systematic review and meta-analysis [PDF]
, 2015 Background: To examine for a possible relationship between osteoarthritis and cardiovascular disease (CVD). Design: A systematic review and meta-analysis Methods: Published and unpublished literature from: MEDLINE, EMBASE, CINAHL, the Cochrane Library ...
Hall, Andrew J. +4 more
core +2 more sources
Scientific Reports, 2021 We compared two and four intra-articular injections of platelet-rich plasma (PRP) in terms of changes of synovial cytokines and clinical outcomes. One hundred twenty-five patients having knee osteoarthritis (OA) underwent PRP injections at a 6-week ...
Srihatach Ngarmukos +11 more
doaj +1 more source
RMD Open, 2022 Elite athletes are at greater risk of joint injuries linked to the subsequent risk of developing osteoarthritis (OA). Genetic factors such as mitochondrial (mt) DNA haplogroups have been associated with the incidence/progression of OA and athletic ...
Jean-Pierre Pelletier +1 more
doaj +1 more source
The potential for dietary factors to prevent or treat osteoarthritis [PDF]
, 2014 Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping +8 more
core +1 more source
Memory CD8+ T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals
Frontiers in Immunology, 2019 Memory CD8+ cytotoxic T lymphocytes (CTLs) can protect against viral reinfection. However, the signals driving rapid memory CTL reactivation have remained ill-defined.
Claudia Baumann +10 more
doaj +1 more source
Pathophysiology of osteoarthritis [PDF]
Osteoarthritis and Cartilage, 1998 Osteoarthritis (OA) is characterized by a degeneration of articular cartilage, in which the breakdown leads to matrix fibrillation, fissure appearance, gross ulceration, and fullthickness loss of the joint surface. This is accompanied by hypertrophic bone changes with osteophyte formation and subchondral bone plate thickening.
openaire +6 more sources
Mild acetabular dysplasia and risk of osteoarthritis of the hip : a case-control study [PDF]
, 2010 Objective To determine whether mild variation in acetabular depth (AD) and shape is a risk factor for osteoarthritis (OA) of the hip. Methods The unaffected contralateral hip of patients with unilateral hip OA was compared with hips of asymptomatic ...
Doherty, Michael +6 more
core +1 more source