Results 21 to 30 of about 708,008 (375)

The Complexity of Human Walking: A Knee Osteoarthritis Study [PDF]

, 2014
This study proposes a framework for deconstructing complex walking patterns to create a simple principal component space before checking whether the projection to this space is suitable for identifying changes from the normality.
Duffell, LD, Faisal, AA, Kotti, M, McGregor, AH   +3 more
core   +5 more sources

In silico targeting of interleukin-6 by natural compounds

Bangladesh Journal of Pharmacology, 2014
Rheumatoid arthritis an autoimmune disorder affecting many tissues and organs, is a challenging prospect in terms of treatment. Our work is looking into finding lead compound of natural origin against IL-6, an important cyto-kine having a profound role ...
Wei Zhou, Jun-Feng Cai, Feng Yuan, Min Ma, Feng Yin   +4 more
doaj   +1 more source

Two or four injections of platelet-rich plasma for osteoarthritic knee did not change synovial biomarkers but similarly improved clinical outcomes

Scientific Reports, 2021
We compared two and four intra-articular injections of platelet-rich plasma (PRP) in terms of changes of synovial cytokines and clinical outcomes. One hundred twenty-five patients having knee osteoarthritis (OA) underwent PRP injections at a 6-week ...
Srihatach Ngarmukos, Chotetawan Tanavalee, Chavarin Amarase, Suphattra Phakham, Warayapa Mingsiritham, Rangsima Reantragoon, Nitigorn Leearamwat, Thidarat Kongkaew, Kittipan Tharakhet, Sittisak Honsawek, Sinsuda Dechsupa, Aree Tanavalee   +11 more
doaj   +1 more source

Acupuncture randomized trials (ART) in patients with chronic low back pain and osteoarthritis of the knee - Design and protocols [PDF]

, 2003
Background: We report on the study design and protocols of two randomized controlled trials (Acupuncture Randomized Trials = ART) that investigate the efficacy of acupuncture in the treatment of chronic low back pain and osteoarthritis of the knee ...
Becker-Witt, C., Brinkhaus, Benno, Hummelsberger, J., Irnich, D., Jena, S., Linde, K., Melchart, Dieter, Streng, A., Wagenpfeil, S., Willich, S. N.   +9 more
core   +1 more source

Update on osteoarthritis part 1: current concepts and the relation to exercise [PDF]

, 2002
There appears to be an increased risk of lower limb osteoarthritis in participants of repetitive, high impact sports, and this is strongly associated with joint injury. There seems to be little risk associated with recreational running.
Conaghan, P.
core   +2 more sources

Memory CD8+ T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals

Frontiers in Immunology, 2019
Memory CD8+ cytotoxic T lymphocytes (CTLs) can protect against viral reinfection. However, the signals driving rapid memory CTL reactivation have remained ill-defined.
Claudia Baumann, Claudia Baumann, Anja Fröhlich, Anja Fröhlich, Tobias M. Brunner, Tobias M. Brunner, Vivien Holecska, Vivien Holecska, Daniel D. Pinschewer, Max Löhning, Max Löhning   +10 more
doaj   +1 more source

A continuous data driven translational model to evaluate effectiveness of population-level health interventions: case study, smoking ban in public places on hospital admissions for acute coronary events

Journal of Translational Medicine, 2020
Background An important task in developing accurate public health intervention evaluation methods based on historical interrupted time series (ITS) records is to determine the exact lag time between pre- and post-intervention.
Hossein Bonakdari, Jean-Pierre Pelletier, Johanne Martel-Pelletier   +2 more
doaj   +1 more source

Is there a mitochondrial DNA haplogroup connection between osteoarthritis and elite athletes? A narrative review

RMD Open, 2022
Elite athletes are at greater risk of joint injuries linked to the subsequent risk of developing osteoarthritis (OA). Genetic factors such as mitochondrial (mt) DNA haplogroups have been associated with the incidence/progression of OA and athletic ...
Jean-Pierre Pelletier, Johanne Martel-Pelletier   +1 more
doaj   +1 more source

Mass spectrometry-based proteomics identify novel serum osteoarthritis biomarkers

Arthritis Research & Therapy, 2022
Background Osteoarthritis (OA) is a slowly developing and debilitating disease, and there are no validated specific biomarkers for its early detection.
Ginette Tardif, Frédéric Paré, Clarisse Gotti, Florence Roux-Dalvai, Arnaud Droit, Guangju Zhai, Guang Sun, Hassan Fahmi, Jean-Pierre Pelletier, Johanne Martel-Pelletier   +9 more
doaj   +1 more source

The genetic contribution to severe post-traumatic osteoarthritis [PDF]

, 2013
Objective: to compare the combined role of genetic variants loci associated with risk of knee or hip osteoarthritis (OA) in post-traumatic (PT) and non-traumatic (NT) cases of clinically severe OA leading to total joint replacement.
Ana M Valdes, Anderson, arcOGEN Consortium and arcOGEN Collaborators, Brown, Castaño-Betancourt, Day-Williams, Dieppe, Doherty, Englund, Evangelou, Herrero-Beaumont, Kenneth R Muir, Lopez, Margaret Wheeler, Michael Doherty, Muthuri, Rose A Maciewicz, Sally A Doherty, Sward, Valdes, Valdes, Weiya Zhang   +21 more
core   +1 more source