Results 31 to 40 of about 708,008 (375)
Journal of Translational Medicine, 2023 Background Specialized pro-resolving mediators (SPMs), including 18-HEPE, 17-HDHA, and 14-HDHA are recognized as potentially therapeutic in inflammatory diseases because SPMs regulate the inflammation process, which leads to, for example; swelling and ...
Ingrid Möller +6 more
doaj +1 more source
Femoroacetabular impingement: a cause for osteoarthritis of the hip.
Clinical Orthopaedics and Related Research, 2003 A multitude of factors including biochemical, genetic, and acquired abnormalities may contribute to osteoarthritis of the hip. Although the pathomechanism of degenerative process affecting the dysplastic hip is well understood, the exact pathogenesis for
R. Ganz +5 more
semanticscholar +1 more source
The Validity, Reliability, Measurement Error, and Minimum Detectable Change of the 30‐Second Fast‐Paced Walk Test in Persons with Knee Osteoarthritis: A Novel Test of Short‐Distance Walking Ability [PDF]
, 2019 Objective To develop and establish the reliability, validity, measurement error, and minimum detectable change of a novel 30‐second fast‐paced walk test (30SFW) in persons with knee osteoarthritis (OA) that is easy to administer and can quantify walking ...
Folkins, DPT, Erik +3 more
core +2 more sources
Arthritis Research & Therapy, 2018 Background The aim of this study was to measure the association between exposure to commonly used oral osteoarthritis (OA) therapies and relevant confounding risk factors on the occurrence of knee replacement (KR), using the Osteoarthritis Initiative ...
Marc Dorais +4 more
doaj +1 more source
STING mediates experimental osteoarthritis and mechanical allodynia in mouse
Arthritis Research & Therapy, 2023 Background This study was performed to develop therapeutic targets of osteoarthritis (OA) that can be targeted to alleviate OA development (i.e., cartilage destruction) and relieve the OA-associated joint pain.
Youngnim Shin +3 more
doaj +1 more source
Scientific Reports, 2021 Sports-related injuries increase healthcare cost burden, and in some instances have harmful long term physical and psychological implications. There is currently a lack of comprehensive data on temporal injury trends across professional North American ...
Garrett S. Bullock +3 more
doaj +1 more source
Pulsed electromagnetic energy treatment offers no clinical benefit in reducing the pain of knee osteoarthritis: a systematic review [PDF]
, 2006 Background The rehabilitation of knee osteoarthritis often includes electrotherapeutic modalities as well as advice and exercise. One commonly used modality is pulsed electromagnetic field therapy (PEMF).
AD Woolf +22 more
core +5 more sources
Arthritis Research & Therapy, 2017 Background There is an obvious need to identify biomarkers that could predict patient response to an osteoarthritis (OA) treatment. This post hoc study explored in a 2-year randomized controlled trial in patients with knee OA, the likelihood of some ...
Johanne Martel-Pelletier +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 D prostanoid receptor 1 (DP1), a prostaglandin D2 receptor, plays a central role in the modulation of inflammation and cartilage metabolism. We have previously shown that activation of DP1 signaling downregulated catabolic responses in cultured ...
Mehdi Najar +9 more
doaj +1 more source
Arthroscopic washout of the knee: a procedure in decline. [PDF]
, 2014 BACKGROUND: Osteoarthritis (OA) of the knee is a chronic, progressive condition which often requires surgical intervention. The evidence for the benefits of arthroscopic debridement or washout for knee OA is weak and arthroscopy is currently only ...
American Academy of Orthopaedic Surgeons +28 more
core +1 more source