Results 71 to 80 of about 693,773 (371)

Comprehensive comparative analysis of infrapatellar fat pad morphologies in a longitudinal knee osteoarthritis exploratory study: new insights into its role as an independent prognostic marker

Arthritis Research & Therapy
Background No established markers can effectively phenotype knee osteoarthritis (OA) patients into subgroups. Infrapatellar fat pad (IPFP) morphology data that can forecast disease symptoms, structural changes, and knee replacement (KR) are sparse and ...
Jean-Pierre Pelletier, Patrice Paiement, François Abram, Marc Dorais, Jean-Pierre Raynauld, Johanne Martel-Pelletier   +5 more
doaj   +1 more source

Global, regional, and national burdens of hip osteoarthritis from 1990 to 2019: estimates from the 2019 Global Burden of Disease Study

Arthritis Research & Therapy, 2022
Background Hip osteoarthritis is a common disabling condition of the hip joint and is associated with a substantial health burden. We assessed the epidemiological patterns of hip osteoarthritis from 1990 to 2019 by sex, age, and socio-demographic index ...
Ming-Nian Fu, Hongming Zhou, Yushi Li, Hai Jin, Xiqing Liu   +4 more
semanticscholar   +1 more source

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source

Future directions for the management of pain in osteoarthritis. [PDF]

, 2014
Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA
Aigner T, Anasuya Kuttapitiya, Balanescu AR, Bannuru RR, Chou R, da Costa BR, Danielsson L, Fanelli A, Fransen M, Haviv B, Huskisson EC, Lim YZ, Mankin HJ, McAlindon TE, Merlotti D, Nguyen US, Nidhi Sofat, Pelletier JP, Sagar DR, Sellers RS, Sofat N, Tannenbaum H, Wajed J, Wakitani S   +23 more
core   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Upregulated endonuclease Regnase-1 suppresses osteoarthritis by forming a negative feedback loop of catabolic signaling in chondrocytes

Arthritis Research & Therapy, 2021
Background Ribonucleases (RNases) play central roles in the post-transcriptional regulation of mRNA stability. Our preliminary results revealed that the endonuclease Regnase-1 is specifically upregulated in osteoarthritic chondrocytes. We herein explored
Jeong-In Yang, Jang-Soo Chun
doaj   +1 more source

Association of presurgical circulating MicroRNAs with 1-year postsurgical pain reduction in spine facet osteoarthritis patients with lumbar spinal stenosis

Osteoarthritis and Cartilage Open, 2022
Purpose: Up to 30% of spine facet osteoarthritis patients with lumbar spinal stenosis (SF-OA ​+ ​LSS) have little to no improvement in their pain after surgery.
Starlee Lively, Marie Milliot, Pratibha Potla, Osvaldo Espin-Garcia, Mehdi Layeghifard, Kala Sundararajan, Helal Endisha, Akihiro Nakamura, Anthony V. Perruccio, Christian Veillette, Mohit Kapoor, Y. Raja Rampersaud   +11 more
doaj   +1 more source

Degenerative Meniscus in Knee Osteoarthritis: From Pathology to Treatment

Life, 2022
Knee osteoarthritis is a common degenerative joint disease characterized by chronic knee pain and disability in daily living. The lesion can involve the cartilage as well as the synovium, bone, ligaments, and meniscus, indicating a complicated pathology ...
N. Ozeki, H. Koga, I. Sekiya
semanticscholar   +1 more source

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. [PDF]

, 2015
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With obesity on the rise and the worlds population living longer,
Bhatti, Simi, Christiansen, Blaine, Emami, Shahin, Goudarzi, Ramin   +3 more
core   +1 more source

Proportion of Acceptable Symptom State Nearly Tripled With Improvements in Patient‐Reported Outcomes for All Symptom State Subgroups: A Registry Study of More Than 15,000 Patients With Osteoarthritis in Digital Education and Exercise Therapy

Arthritis Care &Research, EarlyView.
Objective This study investigated trajectories of patient acceptable symptom state (PASS) among participants of digital education and exercise therapy for knee and hip osteoarthritis. Methods A longitudinal observational study among individuals aged at least 40 years who participated in the digital program.
Ali Kiadaliri, L. Stefan Lohmander, Amanda E. Nelson, Leif E. Dahlberg   +3 more
wiley   +1 more source