Results 81 to 90 of about 99 (99)

Knee Flexion Excursion Mediates the Association Between Quadriceps Stiffness and Knee Loads During the Mid‐Stance Phase of Gait

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Lower strength and higher passive stiffness of the quadriceps have been associated with a higher risk of knee osteoarthritis/pain in aging populations. It is proposed that altered quadriceps properties would cause excessive knee loads, thus contributing to knee mechanical damages, but the relevant evidence is limited.
Zongpan Li, Aaron Kam‐Lun Leung, Xiuping Huang, Chen Huang, Shan Su, Raymond C. K. Chung, Changhai Ding, Siu Ngor Fu   +7 more
wiley   +1 more source

Tophaceous gout

Journal of Hospital Medicine, EarlyView.
Tyler B. Larsen, Michael E. Lazarus
wiley   +1 more source

Aberrant Gait Biomechanics Linked to Cartilage Changes After ACL Reconstruction in Those With High Body Mass Index

Journal of Orthopaedic Research, EarlyView.
ABSTRACT A history of anterior cruciate ligament reconstruction (ACLR) and high body mass index (BMI) are strong risk factors for incident knee osteoarthritis. Limited research has evaluated the interaction between ACLR and high BMI on limb‐level loading and early deleterious changes in cartilage health.
Hyunwook Lee, Ashley N. Buck, Cortney Armitano‐Lago, Robert A. Creighton, Ganesh M. Kamath, Jeffrey T. Spang, Xiaojuan Li, David Lalush, Jason R. Franz, J. Troy Blackburn, Brian Pietrosimone   +10 more
wiley   +1 more source

Advanced Testing Protocols Simulate Failures and Validate Antioxidant Polyethylene in Ankle Implants

Journal of Orthopaedic Research, EarlyView.
Abstract Total ankle replacement (TAR) has become an effective treatment for end‐stage ankle osteoarthritis. Multiple factors, including patient characteristics, surgical technique, alignment, and bearing surfaces, influence TAR survivorship. Polyethylene (PE) fatigue is a key consideration in improving outcomes.
Ryan Siskey, Patrick Hall, Ruth Heckler, David Safranski, James Johnson, Ariel Palanca   +5 more
wiley   +1 more source

Acute Prolonged Hamstrings Vibration Reduces Limb Stiffness Following Anterior Cruciate Ligament Reconstruction During a Single‐Limb Drop‐Jump Task

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Impaired quadriceps function influences lower limb biomechanics following anterior cruciate ligament reconstruction (ACLR). This often results in stiff limb loading which leads to the development of knee osteoarthritis. Greater hamstrings/quadriceps co‐activation is common after ACLR and is, in part, responsible for impaired quadriceps ...
Timothy Lowe, Hao‐Yuan Hsiao, Xuanliang Neil Dong, Lisa Griffin   +3 more
wiley   +1 more source

Ultrasound Neuromodulation (Low‐Intensity Focused Ultrasound) to Treat Knee Osteoarthritis Pain

Journal of Ultrasound in Medicine, EarlyView.
Low‐intensity focused ultrasound is a non‐invasive neuromodulation technique that delivers mechanical forces to a deep location within the body through acoustic pressure waves without affecting tissue between the transducer and focal target. Preliminary studies involving healthy volunteers suggest focused ultrasound reversibly prevents action potential
Brian M. Ilfeld, Khoa N. Cao, Ruben Branson, Philip Bloom   +3 more
wiley   +1 more source

Circ_0006646 Promotes the Progression of Osteoarthritis via Upregulating CDH11 Expression in an IGF2BP2‐Dependent Manner

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative osteoarthropathy with an unclear pathogenesis. Circular RNA (circRNA) has been reported to be associated with OA progression. This study aims to explore the role and potential mechanism of hsa_circ_0006646 in OA. Interleukin‐1β (IL‐1β)‐induced human chondrocytes were used as the cell model of OA. RT‐
Ming‐Yu Hua, Guo‐Liang Wang, Wen‐Hao Duan, Xiao‐Heng Tang   +3 more
wiley   +1 more source

Monotropein Induced Ferroptosis to Alleviate the Progression of Hepatocellular Carcinoma via Regulating Nrf2/HO‐1/GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) exhibits a high global morbidity rate and ranks as the fourth leading cause of cancer‐related mortality worldwide. In response to the urgent need for effective HCC treatments, naturally occurring, botanical‐driven compounds have gained increasing attention.
Bing Shi, Yan‐Ping Li, Zhuo Gan, Pan Chen   +3 more
wiley   +1 more source

No difference in osteoarthritis, but less graft failures after 5 years, comparing anatomic double‐bundle to anatomic single‐bundle ACL reconstruction

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this study was to compare the incidence of knee osteoarthritis (OA) between the anatomic single‐bundle (SB) and anatomic double‐bundle (DB) anterior cruciate ligament (ACL) reconstruction technique after 5‐year follow‐up (FU).
Cathrine Aga, Ingrid Trøan, Stig Heir, May Arna Risberg, Tariq Rana, Steinar Johansen, Morten Wang Fagerland, Lars Engebretsen   +7 more
wiley   +1 more source

Adapting the Dejour classification of trochlear dysplasia from qualitative radiograph‐ and CT‐based assessments to quantitative MRI‐based measurements

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To adapt the current D. Dejour trochlear dysplasia classification (v2.0) to only rely on quantitative magnetic resonance imaging (MRI) measurements (v3.0) to maximize objectivity and repeatability. Methods A consecutive series of adult knee MRIs were divided into objective patellar instability (OPI, n = 127) or controls (n = 103 ...
David H. Dejour, Edoardo Giovanetti de Sanctis, Jacobus H. Müller, Etienne Deroche, Tomas Pineda, Amedeo Guarino, Cécile Toanen, Patellofemoral Imaging Group, Andrea Amarossi, Alexandre Baujard, Nicolas Cance, Julien Dartus, Paolo Ferrua, Stefano Pasqualotto, Francesco Puglia, Sophie Putman, Mo Saffarini   +16 more
wiley   +1 more source