Results 171 to 180 of about 497,266 (304)

Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics. [PDF]

Heliyon
Pakdaman Kolour SS, Nematollahi S, Dehbozorgi M, Fattahi F, Movahed F, Esfandiari N, Kahrizi MS, Ghavamikia N, Hajiagha BS.   +8 more
europepmc   +1 more source

Posterior tibial slope measurement on lateral radiographs shows increased variability, reduced repeatability and risk of misclassification in osteoarthritic versus nonosteoarthritic knees

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The primary aim was to compare the variability and repeatability of medial posterior tibial slope (MPTS) measurements on lateral knee radiographs between osteoarthritic (OA) and non‐OA knees, and the secondary aim was to assess their implications for clinical classification.
Moses Kamal Dieter El Kayali, Luis Vincent Bürck, Clemens Gwinner, Lorenz Pichler, Alan Getgood, Mo Saffarini, Rosa Berndt   +6 more
wiley   +1 more source

Utilising Discriminant Function Analysis (DFA) for Classifying Osteoarthritis (OA) Patients and Volunteers Based on Biomarker Concentration. [PDF]

Diagnostics (Basel)
Coleman LJ, Byrne JL, Edwards S, O'Hara R.   +3 more
europepmc   +1 more source

Gait alterations increase friction of degenerated articular cartilage: A tribological study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To investigate the effect of gait alterations associated with osteoarthritis (OA) on the frictional properties of porcine articular cartilage (AC) in intact and degenerative conditions. Methods Forty‐eight cylindrical AC samples were harvested from 12 porcine femur condyles and equally divided between four groups with n = 12 samples ...
Luisa de Roy, Graciosa Quelhas Teixeira, Maria Ahrens, Benjamin Mayer, Cornelia Horsch, Anita Ignatius, Andreas Martin Seitz   +6 more
wiley   +1 more source

Intra-articular injection of miRNA-1 agomir, a novel chemically modified miRNA agonists alleviates osteoarthritis (OA) progression by downregulating Indian hedgehog in rats. [PDF]

Sci Rep
Li P, Gao Y, Zhou R, Che X, Wang H, Cong L, Jiang P, Liang D, Li P, Wang C, Li W, Sang S, Duan Q, Wei X.   +13 more
europepmc   +1 more source

Safety profile comparison of intra‐articular corticosteroids, hyaluronic acid, platelet‐rich plasma, and cell‐based injections for knee osteoarthritis: A systematic review and meta‐analysis by the ESSKA Orthobiologics Initiative

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim was to compare the safety profiles of corticosteroids (CS), hyaluronic acid (HA), blood‐derived products based on platelet concentrates (for simplicity indicated as PRP ‐ platelet‐rich plasma ‐ being PRP the most common product), and cell‐based therapies (namely products exploiting the therapeutic function of mesenchymal ...
Alessandro Bensa, Andrea Piano, Giacomo Arthur Fumagalli, Laura de Girolamo, Lior Laver, Jérémy Magalon, Mikel Sánchez, Thomas Tischer, Giuseppe Filardo   +8 more
wiley   +1 more source

Ten‐year outcomes of combined ACLR and lateral extra‐articular tenodesis: A systematic review

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This systematic review evaluates long‐term outcomes after anterior cruciate ligament reconstruction (ACLR) with lateral extra‐articular tenodesis (LET), including patient‐reported outcome measures (PROMs), failure rates, objective knee scores and radiographic osteoarthritis (OA).
Marc Daniel Bouchard, Omar Haque, Michelle Cruickshank, Prushoth Vivekanantha, Sachin Tapasvi, Amit Meena, Darren de Sa   +6 more
wiley   +1 more source

Clinical validation of fully automated laminar knee cartilage transverse relaxation time (T2) analysis in anterior cruciate ligament (ACL)-injured knees- on behalf of the osteoarthritis (OA)-Bio consortium. [PDF]

Quant Imaging Med Surg
Eckstein F, Brisson NM, Maschek S, Wisser A, Berenbaum F, Duda GN, Wirth W.   +6 more
europepmc   +1 more source

Managing the meniscus part I—Anatomy, biomechanics, and treatment strategies for the atraumatic meniscus tear

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this article is to serve as the first of a two‐part review on the meniscus; in this review, we will establish the background on anatomy and pathogenesis of the meniscus, as well as the effect of the meniscus on native knee kinematics and function.
Ehab M. Nazzal, Jonathan D. Hughes, Armin Runer, Matthew P. Kolevar, Jorge Chahla, Robert G. Marx, James J. Irrgang, Roman Seil, Berte Bøe, David Parker, Ryosuke Kuroda, Eric H. Senorski, Sachin Tapasvi, Volker Musahl   +13 more
wiley   +1 more source

Managing the meniscus Part 2: Traumatic tear patterns, biologic augmentation, transplantation, innovation and future research

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Acute, traumatic meniscus tears are common and should be repaired whenever possible. However, the biological age of the patient, along with the specific tear morphology, may significantly influence the selection of the repair technique, expected clinical outcomes and the postoperative rehabilitation protocol.
Armin Runer, Matthew P. Kolevar, Ehab M. Nazzal, Jonathan D. Hughes, Sebastian Kopf, Aaron J. Krych, Michael T. Hirschmann, Robert F. LaPrade, Alan Getgood, Tim Spalding, Robert Prill, Maria Tuca, Matthieu Ollivier, Sebastian Siebenlist, Sachin Tapasvi, Volker Musahl   +15 more
wiley   +1 more source