Results 191 to 200 of about 126,184 (308)

An exploratory Mendelian randomization study on the genetically predicted effects of circulating blood cells on osteoarthritis risk. [PDF]

Clinics (Sao Paulo)
Zhou L, Jia J, Chen X, Chen T.
europepmc   +1 more source

Adipose‐derived and bone marrow aspirate concentrate injections for osteoarthritis: A scoping review

PM&R, EarlyView.
Abstract Background Osteoarthritis is a leading cause of disability worldwide, and cell‐based treatments including adipose‐derived and bone marrow aspirate have been sought by the lay and medical community as treatment options. Objective To perform a scoping review of published literature on cell‐based injections allowed by the U.S.
Leonardo P. Oliveira, Aaron Lear, Joseph Elphingstone, Derek Stokes, Rachel Chamberlain, Timothy Tiu, David Price, Megan Agnew, Stephanie Kliethermes, Sarah Sund, Leslie A. Christensen, Shane Shapiro, Kenneth Mautner   +12 more
wiley   +1 more source

Prevalence of hip and elbow dysplasia in young adult dogs in Sweden

Veterinary Record, EarlyView.
Abstract Background Hip and elbow dysplasia (HD and ED) are common developmental orthopaedic disorders in dogs. The study objectives were to report population‐based estimates of HD and ED prevalence at screening in young adult dogs of different breeds and to evaluate the phenotypic association between HD and ED.
Karolina Engdahl, Sofia Malm Persson, Linda Andersson, Sara Ringmark, Charlotte Reinhard Bjørnvad, Åke Hedhammar, Katja Höglund   +6 more
wiley   +1 more source

Prospective comparison of chronic pain and quality of life in dogs presenting with five common orthopaedic conditions

Veterinary Record, EarlyView.
Abstract Background Chronic pain, which affects multiple aspects of dogs' wellbeing, including quality of life (QoL), was assessed in dogs with elbow dysplasia, hip dysplasia, medial patella luxation, cranial cruciate ligament rupture or osteoarthritis.
Christos Dorlis, Dylan N. Clements, John M. Ryan   +2 more
wiley   +1 more source

Methodological considerations on "Serum TSP-1 is a useful biomarker in severity assessment and the diagnosis of osteoarthritis". [PDF]

J Transl Med
Chen J, Chu Y.
europepmc   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Plain Language Summary of a Phase 2 Study of Triamcinolone Acetonide Extended-Release for Pain Relief in People With Knee Osteoarthritis and Type 2 Diabetes. [PDF]

Ther Adv Musculoskelet Dis
Spitzer AI, Rodbard H.
europepmc   +1 more source

Evaluating Hip Osteoarthritis as a Risk Factor for Immune Checkpoint Inhibitor-Induced Inflammatory Arthritis. [PDF]

J Rheumatol
Fitzpatrick R, Demehri S, Murray J, Brahmer JR, Ghotbi E, Barasa D, Bingham CO, Shah AA, Cappelli LC.   +8 more
europepmc   +1 more source

A critical appraisal of the safety of bedinvetmab (Beransa), a canine antinerve growth factor monoclonal antibody

Australian Veterinary Journal, EarlyView.
Clinical scenario Canine osteoarthritis (OA) is a degenerative joint disease and is one of the most common chronic conditions in dogs and other species. The management of OA remains a longstanding focus in veterinary medicine. Traditionally, nonsteroidal anti‐inflammatory drugs (NSAIDs) have been the first‐line treatment option for canine OA. Recently,
X Yang, P Macarthur
wiley   +1 more source

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

Cell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu, Sheng‐Jie Chang, Shuo Wang, Xiao‐Wei Liu, Shan‐Jin Wang   +4 more
wiley   +1 more source