Results 201 to 210 of about 126,184 (308)

End-Stage Ankle Osteoarthritis: Exploring the Precedent Causes and Time Course of Joint Degeneration. [PDF]

JB JS Open Access
de Cesar Netto C, Cychozs C, Barbachan Mansur NS, Auch E, Lorentzen W, Chrea B, Lintz F, Anderson D.   +7 more
europepmc   +1 more source

Pleiotropic roles of metallothioneins in osteoarthritis(oa) pathogenesis

Osteoarthritis and Cartilage, 2017
Y. Won, Y. Shin, J.-S. Kwak, W.-K. Song, J.-S. Chun   +4 more
openaire   +1 more source

Light‐Inducible Activation of FGFR3 Facilitates Chondrocyte Maturation

Cell Proliferation, EarlyView.
Light‐inducible activation of FGFR3 induced robust activation of MAPK signaling, promoting proliferation and collagen depositon in induced chondrocytes and prevent the degeneration of osteoarthritic chondrocytes.
Mengze Sun, Yun Zhao, Yuqing Du, Yifei Fan, Kai Wang, Xiaoqing Hu   +5 more
wiley   +1 more source

Factors Associated With Functional Outcomes in Former Professional American-Style Football Players With Symptomatic Knee and Hip Osteoarthritis. [PDF]

Orthop J Sports Med
Bruneau MM, Grashow R, Gaudette L, Weisskopf MG, Whittington AJ, Taylor HA, Wasfy M, Speizer FE, Zafonte R, Baggish A, Borg-Stein J, Tenforde AS.   +11 more
europepmc   +1 more source

Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the associations between semaglutide initiation and long‐term skeletal outcomes in people with obesity, stratified by type 2 diabetes (T2D) status, using target trial emulation. Materials and Methods This retrospective cohort study used the TriNetX federated electronic health record network.
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Shao‐Chia Chen, Hao‐I Hsieh, Gideon Meyerowitz‐Katz, Yen‐Liang Liu, Pen‐Hua Su   +8 more
wiley   +1 more source

CircFN1 modulates IL-1β-induced osteoarthritis through the miR-19b-3p/PTEN signaling axis. [PDF]

Sci Rep
Jiang Y, Wang Q, Yang X, Liu H, Wu H, Wang M, Pan L, Cao Y, Meng Z.   +8 more
europepmc   +1 more source

Metabolomic Signatures of Dietary Patterns and Incident Radiographic Knee Osteoarthritis: A Case-Cohort Study From the Osteoarthritis Initiative. [PDF]

J Rheumatol
Xu S, Driban JB, Prakash PS, McAlindon TE, Eaton CB, Lu B.   +5 more
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

C-reactive protein-triglyceride glucose index is a reliable biomarker for osteoarthritis: A cross-sectional study based on NHANES 1999-2018. [PDF]

Medicine (Baltimore)
Xie R, Long J, Liu D.
europepmc   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source