Harnessing bacterial extracellular vesicles for bone and cartilage organoids
BMEMat, EarlyView.This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu +8 more
wiley +1 more source
Mechanical Unloading Inhibits Osteoblast Differentiation via Downregulation of OGT-Mediated O-GlcNAcylation. [PDF]
Curr Issues Mol BiolZhao X +13 more
europepmc +1 more source
Subperiosteal peri‐implant augmented layer to correct bone dehiscence at immediate implant placement
Clinical Advances in Periodontics, EarlyView.Abstract Background The purpose of the present case report is to describe the potential of the subperiosteal peri‐implant augmented layer (SPAL) technique in peri‐implant bone dehiscence (PIBD) correction at immediate implant placement (IIP). Methods This case report describes the application of the SPAL technique in two patients undergoing IIP at ...
Tommaso Grenzi +3 more
wiley +1 more source
Clinical Advances in Periodontics, EarlyView.Background CAD/CAM zirconia barriers represent an advanced option for guided bone regeneration (GBR) in three‐dimensional defects, integrating mechanical stability, biocompatibility, and digital precision. The objectives of this case series were to evaluate, clinically, histologically, and three‐dimensionally, the use of customized zirconia barriers ...
Roberto Ledergerber +5 more
wiley +1 more source
SCF<sup>JFK</sup> regulates osteoblast differentiation through targeting RUNX2. [PDF]
Signal Transduct Target TherShang Z +13 more
europepmc +1 more source
Role of SoxE transcription factors in development and disease
Developmental Dynamics, EarlyView.Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley +1 more source
Decoding Skeletal Biology Through Transcriptomics: Insights from Bulk, Single-Cell, Spatial, and Multi-Omics Approaches. [PDF]
Int J Mol SciAli Z +4 more
europepmc +1 more source
Secretopathies emerge as a new class of neurocristopathies
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source
Statement of Retraction: Bone mesenchymal stem cells (BMSCs)-derived exosomal microRNA-21-5p regulates Kruppel-like factor 3 (KLF3) to promote osteoblast proliferation <i>in vitro</i>. [PDF]
Bioengineeredeuropepmc +1 more source
Prmt6 Deficiency Drives Osteoblast Senescence Promoting Age-Related Osteoporosis via Epigenetic Remodelling of the H3R2me2a/Sting/Ifitm3 Pathway. [PDF]
J Cell Mol MedWang Y +7 more
europepmc +1 more source