Results 171 to 180 of about 172,466 (303)

Osteocyte Cell-Cell Communication Within and Beyond Bone. [PDF]

Curr Osteoporos Rep
Bakker AD, van Santen VJB.
europepmc   +1 more source

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

Arthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid, Samuel Kemble, Oladimeji Abudu, Anella Saviano, Christopher Mahony, Jonathan W. Lewis, Thomas A. Nicholson, Anna Schettino, Noemi Marigliano, Kathryn Frost, Jenefa Begum, Alyssa M. Urbanowski, Marion Limo, Rakesh Jha, Sandra Martinez Jarquin, Laleh Pezhman, Abbie E. A. Degan, Amy E. Anderson, Charlotte G. Smith, Armaiti Batki, Holly Adams, Francesco Caso, Raffaele Scarpa, Iain McInnes, Stefan Siebert, Arthur G. Pratt, Andrew Filer, Karim Raza, Adam P. Croft, Myriam Chimen, Felicity de Cogan, G. Ed Rainger, Asif J. Iqbal, Francesco Maione, Helen M. McGettrick   +34 more
wiley   +1 more source

The Role of Follistatin-like 1 in the Cross-Talk Among Osteoclastogenesis, Bone Marrow Stromal Cell Migration, and Osteoblastogenesis <i>In Vitro</i>. [PDF]

Biomedicines
Piao Y, Che X, Jin X, Lee DK, Park M, Heo EJ, Oh J, Kim SG, Cho DC, Kim HJ, Choi JY.   +10 more
europepmc   +1 more source

Integrin β1 in osteoblast differentiation and migration during acute bone loss after fracture: Regulation of extracellular signal-regulated kinase 1/2 signaling pathway. [PDF]

Cytojournal
Luan J, Li J, Wang J.
europepmc   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

Arthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Constitutive activation of TGF-β receptor type I promotes cortical and cancellous bone formation in adult mice. [PDF]

PLoS One
Chotipinit T, Toejing P, Phetkong C, Sridurongrit S, Leelahavanichkul A, Charles JF, Lotinun S.   +6 more
europepmc   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Molecular role of developmentally regulated GTP-binding protein 1 in coordinating osteoclast and osteoblast differentiation during bone remodeling. [PDF]

Mol Cells
Kim JH, Seong S, Kim K, Kim I, Koh JT, Kim N.   +5 more
europepmc   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

The role and mechanisms of bone microenvironment regulators in osteoporosis: novel intervention strategies for addressing the challenges of aging. [PDF]

Front Endocrinol (Lausanne)
Yao H, Cui Y, Li P, Sun S, Peng C, Wu D.
europepmc   +1 more source