Results 101 to 110 of about 2,079,758 (368)

Effect of Jagged1 on the expression of genes in regulation of osteoblast differentiation and bone mineralization ontology in human dental pulp and periodontal ligament cells

Journal of Oral Biology and Craniofacial Research, 2020
Objective: To define the effect of Jagged1 on the gene expression in osteoblast differentiation, regulation of osteoblast differentiation and regulation of bone mineralization ontology.
Kanokporn Hansamuit, Thanaphum Osathanon, Jaijam Suwanwela   +2 more
doaj   +1 more source

RANKL-RANK signaling regulates osteoblast differentiation and bone formation

Bone Research, 2018
In the recent two decades, it has been well elucidated that receptor activator of nuclear factor-κB ligand (RANKL; also known as TNFSF11) binding to its receptor RANK (also known as TNFRSF11A) drives osteoclast development as the crucial signaling ...
Xu Cao
semanticscholar   +1 more source

Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model. [PDF]

, 2014
The clinical management of bone defects caused by trauma or nonunion fractures remains a challenge in orthopedic practice due to the poor integration and biocompatibility properties of the scaffold or implant material. In the current work, the osteogenic
Barrientos-Durán, Antonio, Carpenter, Ellen M, Malinin, Theodore I, Rodríguez-Manzaneque, Juan Carlos, Zanello, Laura P, Zur Nieden, Nicole I   +5 more
core   +2 more sources

EBF2 Regulates Osteoblast-Dependent Differentiation of Osteoclasts [PDF]

Developmental Cell, 2005
Communication between bone-depositing osteoblasts and bone-resorbing osteoclasts is required for bone development and homeostasis. Here, we identify EBF2, a member of the early B cell factor (EBF) family of transcription factors that is expressed in osteoblast progenitors, as a regulator of osteoclast differentiation. We find that mice homozygous for a
KIESLINGER M, FOLBERTH S, DOBREVA G, DORN T, CROCI L, ERBEN R, CONSALEZ , GIAN GIACOMO, GROSSCHEDL R.   +7 more
openaire   +5 more sources

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Recombinant human secretory leukocyte protease inhibitor (rhSLPI) coated titanium enhanced human osteoblast adhesion and differentiation

Scientific Reports, 2023
Osseointegration is vital to success in orthopedic and dental reconstructions with implanted materials. The bone matrix or cells—particularly osteoblasts—are required to achieve functional contact on the implant surface. Osteoblast induction is therefore
Radchanon Leelasukseree, Wannapat Chouyratchakarn, Chayanisa Phutiyothin, Faprathan Pikwong, Onnicha Srisopar, Phornsawat Baipaywad, Suruk Udomsom, Podsawee Mongkolpathumrat, Chayarop Supanchart, Sarawut Kumphune   +9 more
doaj   +1 more source

Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation

Molecular Medicine Reports, 2017
Mangiferin is a polyphenolic compound present in Salacia reticulata. It has been reported to reduce bone destruction and inhibit osteoclastic differentiation. This study aimed to determine whether mangiferin directly affects osteoblast and osteoclast proliferation and differentiation, and gene expression in MC3T3‑E1 osteoblastic cells and osteoclast ...
Yuusuke Sekiguchi, Hiroshi Mano, Sachie Nakatani, Jun Shimizu, Aya Kataoka, Kana Ogura, Yoshifumi Kimira, Midori Ebata, Masahiro Wada   +8 more
openalex   +5 more sources

An Examination of the Effects of Atorvastatin and Parathyroid Hormone on Osteoblast Activity [PDF]

, 2014
HMG-CoA reductase inhibitors, also known as statins, are a ubiquitous class of medication used for lowering cholesterol. In-vitro and animal studies have suggested that statins can activate osteoblast differentiation and have anabolic effects on bones ...
Lam, InLok, Lull, Melinda E., Traina, Andrea   +2 more
core   +1 more source

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network

, 2006
Several homeodomain (HD) proteins are critical for skeletal patterning and respond directly to BMP2 as an early step in bone formation. RUNX2, the earliest transcription factor proven essential for commitment to osteoblastogenesis, is also expressed in ...
Aberg, Acampora, Afzal, Amjad Javed, Andre J. van Wijnen, Aronow, Bae, Balint, Banerjee, Banerjee, Beanan, Bendall, Bryan, Cheng, Choi, Depew, Depew, Drissi, Drissi, Ducy, Ferrari, Fujita, Gary S. Stein, Gaur, Ghoul-Mazgar, Harris, Hassan, Hoffmann, Ichida, Ishii, Jane B. Lian, Janet L. Stein, Kim, Komori, Lallemand, Lee, Lengner, Lengner, Lundberg, Maria I. Morasso, Matthew Mandeville, McKeown, Miyama, Mohammad Q. Hassan, Nakashima, Newberry, Otto, Owen, Park, Pratap, Provot, Rahul S. Tare, Robinson, Robledo, Roca, Rosen, Ryoo, Satokata, Satokata, Semba, Shirakabe, Smith, Stricker, Suk Hee Lee, Ten Dijke, Vaes, van Gurp, Xu, Yoshizawa, Zaidi, Zaidi, Zambotti   +71 more
core   +1 more source

Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis [PDF]

, 2010
Introduction: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease primarily involving the synovium. Evidence in recent years has suggested that the bone marrow (BM) may be involved, and may even be the initiating site of the disease ...
Bellantuono, I., Coulton, L., Croucher, P.I., Gambardella, A., Hughes, D., Kottam, L., Mohanty, S.T., Nicklin, M.J., Wilson, A.G.   +8 more
core   +3 more sources