HIF1A overexpression promotes osteoblast differentiation through activation of autophagy to alleviate osteoporosis. [PDF]
Qiao J, Liu A, Sun C, Liu Q.
europepmc +1 more source
The regulation of stem cell fate and its application in neural regeneration
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
MECP2 Insufficiency Attenuates RUNX2-Dependent Osteoblast Differentiation via miR-126-3p/DKK1-Mediated Canonical Wnt Signaling Inhibition in Rett Syndrome. [PDF]
Dong S +12 more
europepmc +1 more source
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang +13 more
wiley +1 more source
Correction: The role of vesicle trafficking genes in osteoblast differentiation and function. [PDF]
Zhu H, Su Y, Wang J, Wu JY.
europepmc +1 more source
MicroRNAs identified that regulate osteoblast differentiation
openaire +3 more sources
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis +11 more
wiley +1 more source
METTL3 inhibits osteoporosis by promoting osteoblast differentiation through m6A-mediated activation of the FZD3/RUNX1 signaling axis. [PDF]
Wang Y +5 more
europepmc +1 more source
Abstract Background This randomized controlled trial aims to evaluate alveolar ridge preservation (ARP) with or without a biologically active amnion–chorion membrane (BACM). Methods Thirty patients requiring tooth extraction in the esthetic zone were randomly assigned to 2 groups.
Magdalena Orlowska +8 more
wiley +1 more source
Protein disulfide isomerase is essential for osteoblast differentiation in mice. [PDF]
Lu Y, Yang A, Zhao Z, Han Y, Wu D, Wu Y.
europepmc +1 more source

