Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh +5 more
wiley +1 more source
Deer Antler Extract Promotes Osteoblast Differentiation and Improves Bone Microarchitecture in an Ovariectomy-Induced Osteoporosis Model. [PDF]
Kwon JH, Lee SH, Lee SH, Kim SW, Cho YE.
europepmc +1 more source
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu +10 more
wiley +1 more source
Polydeoxyribonucleotide (PDRN) Selectively Promotes Osteoblast Differentiation Without Affecting Osteoclastogenesis. [PDF]
Jeon Y +9 more
europepmc +1 more source
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li +6 more
wiley +1 more source
Generation of <i>spCAS9</i> expressing human mesenchymal stem cell line to study gene function during osteoblast differentiation. [PDF]
Foessl I +7 more
europepmc +1 more source
Substrate stiffness with different dimensions (2D and 3D) exerts a regulatory role in cellular behaviors, thereby governing cell fate decisions. Biomaterials with tunable stiffness exhibit substantial functional potential for the repair and regeneration of the motor system.
Zhiyuan Lu +6 more
wiley +1 more source
Coriander Honey Accelerates Human Osteoblast Differentiation and Matrix Mineralization via Intracellular Ca<sup>2+</sup> Signaling. [PDF]
Bonsignore G, Ranzato E, Martinotti S.
europepmc +1 more source
Harnessing bacterial extracellular vesicles for bone and cartilage organoids
This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu +8 more
wiley +1 more source
Hyperoside promotes osteoblast differentiation by increasing osteoclast-derived migrasomes to alleviate osteoporosis. [PDF]
Yan S +5 more
europepmc +1 more source

