Results 261 to 270 of about 2,079,758 (368)

EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma–Induced Epigenetic Suppression of Osteoblast Differentiation

Molecular Cancer Research, 2017
Juraj Adamik, Shun-qian Jin, Quanhong Sun, Peng Zhang, K. Weiss, Judith L. Anderson, R. Silbermann, G. Roodman, D. Galson   +8 more
semanticscholar   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, EarlyView.
ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

Dose-Dependent Effects of TGF-β Inhibition on Osteoblast Differentiation and Wound Healing. [PDF]

Curr Issues Mol Biol
Almuraikhi N, Alkhamees L, Tareen S, Alshammari H, Muthurangan M.   +4 more
europepmc   +1 more source

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

Advanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang, Chenle Dong, Lefeng Su, Zhiqiang Liu, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang, Jiandong Yuan   +11 more
wiley   +1 more source

Naringin promotes osteoblast differentiation and ameliorates osteoporosis in ovariectomized mice. [PDF]

Sci Rep
Cui Y, Yang Z, Yu G, Hu J, Li D, Fu X, Yang W, Yang F.   +7 more
europepmc   +1 more source

A novel mechanism for the regulation of osteoblast differentiation: Transcription of periostin, a member of the fasciclin I family, is regulated by the bHLH transcription factor, twist [PDF]

, 2002
Akira Oshima, Hideyuki Tanabe, Tao Yan, Gina Lowe, Carlotta A. Glackin, Akira Kudō   +5 more
openalex   +1 more source

Osteoblast Differentiation and Bone Matrix Formation In Vivo and In Vitro

Tissue engineering. Part B, Reviews, 2016
H. Blair, Q. Larrouture, Yanan Li, Hang Lin, Donna Beer-Stoltz, Li Liu, R. Tuan, L. Robinson, P. Schlesinger, D. Nelson   +9 more
semanticscholar   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Distinct Functions of Sox2 Control Self-Renewal and Differentiation in the Osteoblast Lineage [PDF]

, 2011
Eunjeong Seo, Upal Basu-Roy, Jiří Zavadil, Claudio Basilico, Alka Mansukhani   +4 more
openalex   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source