Results 91 to 100 of about 1,211,688 (156)

The regulatory networks and mechanisms of bone microenvironment in tumorigenesis and metastasis

Journal of Bone Oncology
Bone tumors, encompassing heterogeneous primary and metastatic lesions, are driven in their initiation, progression, and metastasis by dysregulation of the bone microenvironment (BME).
Guofang Huang, Tianhui Hou, Dianwen Song, Tong Meng   +3 more
doaj   +1 more source

Physiopathology of Spine Metastasis

, 2011
The metastasis is the spread of cancer from one part of the body to another. Two-thirds of patients with cancer will develop bone metastasis. Breast, prostate and lung cancer are responsible for more than 80% of cases of metastatic bone disease.
Carlo Perisano, Calogero Graci, Michele Attilio Rosa, Sigismondo Mauro, Giulio Maccauro, Maria Silvia Spinelli, Perisano C, Maccauro G, ROSA, Michele Attilio, Graci C, Spinelli MS, Mauro S   +11 more
core   +1 more source

Sclerotic Bone Metastasis in Pulmonary Adenocarcinoma

, 2018
Pulmonary adenocarcinoma is one of the major types of lung cancers in which metastasis is very common and it accounts approximately to one-third of all primary pulmonary cancers.
Riyadh Ali Mohammed Hammamy, Khalid Farooqui, Wisam Ghadban   +2 more
core   +1 more source

The role of osteoblast cells in the pathogenesis of unicameral bone cysts

, 2012
PurposeThe pathogenesis of unicameral bone cysts (UBCs) remains largely unknown. Osteoclasts have been implicated, but the role of osteoblastic cells has, to date, not been explored.
Tayton, Edward R, Fowler, Darren J., Edward D. Gent, Richard O. C. Oreffo, Smith, James O., Oreffo, Richard O.C., Caroline J. Edwards, Edward R. Tayton, James O. Smith, Aarvold, Alexander, Darren J. Fowler, Gent, Edward D., Edwards, Caroline J., Alexander Aarvold   +13 more
core   +1 more source

Upregulated bone morphogenetic protein 8A (BMP8A) in triple negative breast cancer (TNBC) and its involvement in the bone metastasis

Frontiers in Cell and Developmental Biology
ObjectiveThe present study aimed to investigate the involvement of aberrant BMP8A expression in TNBC and bone metastasis.MethodsAberrant expression of BMP8A in breast cancer was first determined by analyzing The Cancer Genome Atlas breast cancer cohort ...
Laijian Sui, Laijian Sui, Yizi Cong, Ming Liu, Xiangyi Liu, Yali Xu, Wen G. Jiang, Lin Ye   +7 more
doaj   +1 more source

Effects of etidronate disodium (EHDP) on urogenital malignancies with bone metastasis: a multicentered collaborative evaluation [PDF]

, 1988
Clinical effects of EHDP on relief of bone pain, changes in bone lesions on X-ray and 99mTc-MDP scintigram and performance status were investigated in 19 patients with bone metastasis from urogenital cancers (4 renal cell cancers, 1 renal pelvic cancer ...
柳川, 真, 川村, 寿一, 斉藤, 薫, 森, 脩, 小松, 洋輔, 畑山, 忠, 吉田, 修, 鈴木, 紀元, 栃木, 宏水, 飛田, 収一, 中川, 清秀   +10 more
core  

Mechanisms of Bone Metastasis of Malignancies of the Genito-Mammary Area

, 2018
Bone metastasis is a frequent complication of advanced genito-mammary cancer patients. Skeletal involvement is particularly common in breast cancer. Bone metastases induce a wide range of symptoms, lowering the quality of life and shortening survival ...
T.A. Georgescu, M.M. Cîrstoiu, N. Turcan, R. Bohîlțea   +3 more
core   +1 more source

Wnt1 induces osteoblastic changes in a well-established osteolytic skeletal metastatic model derived from breast cancer.

Osteoblastic skeletal metastasis is frequently observed in prostate cancer. An effective therapy has not been developed due to the unclear molecular mechanism. The Wnt family is involved in various biological phenomena including bone metabolism. There is
Hitomi Sudo, Tatsuya Higashi, Atsushi Tsuji, Aya Sugyo, Yoshiya Sugiura, Mitsuru Koizumi   +5 more
core  

A spectral CT-derived metrics-based radiomics model in differentiating de novo osteoblastic bone metastasis and bone islands in newly diagnosed cancer patients. [PDF]

Front Oncol
Yang Q, Luo H, Zou L, Yuan C, Ma K, Liu C, Luo D, Liu Z.   +7 more
europepmc   +1 more source

The role of osteoblastic β-adrenergic signaling in breast cancer metastasis to bone

, 2012
Metastases are the primary cause of death in breast cancer patients, most often appearing in the bones. Following treatment of the primary cancer, emotional and psychosocial factors within this population hasten time to recurrence and death, however the ...
Campbell, James Preston
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