Results 101 to 110 of about 42,214 (280)

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

Impact of Denosumab Adherence on Renal Function and Mortality Rates in Type 2 Diabetes Patients With Osteoporosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang, Jian‐Chih Chen, Sung‐Yen Lin, Kun‐Der Lin, Pei‐Shan Ho, Chung‐Hwan Chen, Yin‐Chih Fu, Tien‐Ching Lee   +7 more
wiley   +1 more source

CCAAT/Enhancer-binding Proteins (C/EBP) β and δ Activate Osteocalcin Gene Transcription and Synergize with Runx2 at the C/EBP Element to Regulate Bone-specific Expression [PDF]

, 2002
Soraya Gutiérrez, Amjad Javed, Daniel K. Tennant, Monique van Rees, Martı́n Montecino, Gary S. Stein, Janet L. Stein, Jane B. Lian   +7 more
openalex   +1 more source

Immunological Evaluation of PLLA/GO Scaffolds in Goat Mandibular Bone Regeneration

Macromolecular Bioscience, EarlyView.
PLLA/GO scaffolds interact with bone tissue by modulating the immune response and promoting regeneration in goat mandibles. Histological and immunohistochemical analyses reveal progressive tissue organization, mineral deposition, osteoblastic activity, and angiogenesis over time.
Thamires Santos‐Silva, Fernando Gonçalves da Silva Petrônio, Inácio Silva Viana, Raí André Querino Candelaria, Ana Caroline dos Santos, Paulo Alescio Canola, Luís Gustavo Gosuen G. Dias, Rodrigo da Silva Nunes Barreto, Michel Matar, Marcelo Melo Soares, Maria Angelica Miglino   +10 more
wiley   +1 more source

Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma

The Journal of Pathology, EarlyView.
Abstract Osteoid osteoma and osteoblastoma are non‐malignant bone‐forming tumours of the skeleton, characterised by the presence of irregular trabeculae of woven bone. Rearrangements in FOS, and less frequently FOSB, have recently been identified in osteoid osteoma and osteoblastoma.
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy van den Akker, David GP van IJzendoorn, Harald MM Mikkers, Hailiang Mei, Anne‐Marie Cleton‐Jansen, Marieke L Kuijjer, Karoly Szuhai, Judith VMG Bovée   +10 more
wiley   +1 more source

Leptin Mediated Pathways Stabilize Posttraumatic Insulin and Osteocalcin Patterns after Long Bone Fracture and Concomitant Traumatic Brain Injury and Thus Influence Fracture Healing in a Combined Murine Trauma Model [PDF]

, 2020
Anja Garbe, Frank Graef, Jessika Appelt, Katharina Schmidt‐Bleek, Denise Jahn, Tim Lünnemann, Serafeim Tsitsilonis, Ricarda Seemann   +7 more
openalex   +1 more source

Multifunctional Porous Microshuttles as Scaffolding Components and Carriers of Bioactive Factors in Self‐Assembled Microtissues

Small, EarlyView.
This study introduces multifunctional, bioactive factor‐loaded porous microshuttles fabricated via a one‐step emulsification and chemical etching method. The poly(lactic‐co‐glycolic acid) microshuttles, featuring tunable pore sizes, enable loading and release of bioactive factors, and thereby enhance osteogenic marker expression and promote endothelial
Ke Song, Francesca Giacomini, Esra Güben Kaçmaz, Pamela Habibović, Roman Truckenmüller, Zeinab Niloofar Tahmasebi Birgani   +5 more
wiley   +1 more source

Leveraging Viscosity to Unlock the Osteogenic Potential of BMP‐2 Mimetic DWIVA

Small, EarlyView.
Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP‐2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that the viscous properties of the cellular microenvironment play a crucial role in the mechanosensitive regulation of growth factor activity.
Finlay Cunniffe, Ziyuan Luo, Eva Barcelona‐Estaje, Eva Forrest, Manuel Salmeron‐Sanchez, Marco Cantini   +5 more
wiley   +1 more source

Cement Lines are Stiffer and Harder than Bone but Exhibit Different Mineral–Mechanics Relationships due to Thicker and Shorter Mineral Particles

Small Structures, EarlyView.
Bone's complex hierarchical structure contains many internal interfaces, including the cement line (CL) around osteons. This article shows that the CL is stiffer and harder than surrounding bone but has different mineral–mechanics relationships. These findings challenge the view of the CL as a soft, protective interface and provide insights for ...
Astrid Cantamessa, Victoria Schemenz, Stéphane Blouin, Timothy Volders, Shahrouz Amini, Maximilian Rummler, Jiliang Liu, Andrea Berzlanovich, Richard Weinkamer, Wolfgang Wagermaier, Markus A. Hartmann, Davide Ruffoni   +11 more
wiley   +1 more source

Investigating the effect of zinc supplementation on preventing bone resorption in a weightlessness animal model: An experimental study [PDF]

فصلنامه ابن سینا
Background and aims: Bone biomarkers, such as bone-specific alkaline phosphatase (BAP) and osteocalcin (OC), are crucial for researching and monitoring the effects of therapeutic interventions.
Reza Eslami, Amir Khoshvaghti, Kamyab Alizadeh   +2 more
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