Results 81 to 90 of about 79,934 (285)

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Histochemical detection of osteocalcin in normal and pathological human bone. [PDF]

, 1989
We investigated the immunohistochemical localization of osteocalcin in demineralized, paraffin-embedded normal and pathological human bone. Acid decalcification protocols appeared to be more suitable for osteocalcin detection than mild chelating agents.
C Vermeer, F T Bosman, A H Vermeulen
core   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

The quantification of gammacarboxyglutamic acid residues in plasma-osteocalcin [PDF]

, 1988
In this paper we describe an assay procedure for determining the amount of gammacarboxyglutamic acid (Gla) residues in serum- or plasma-osteocalcin. The test includes removing by ethanol precipitation the majority of the proteins from the plasma (e.g ...
Vermeer, Cees, van Haarlem, L. Johan M., Soute, Berry A.M., Ulrich, Magda M.W., Knapen, Marjo H.J.   +4 more
core   +1 more source

Serum osteocalcin and bone mineral density in postmenopausal women [PDF]

Universa Medicina, 2011
Since high bone turnover is associated with decreased bone mass, biochemical markers of bone remodeling, such as serum osteocalcin, may be used to assess osteoporosis and to predict fractures in elderly women, particulary those involving trabecular bone,
Lie T. Merijanti Susanto
doaj  

First-degree family history of diabetes and its relationship with serum osteocalcin levels independent of liver fat content in a non-diabetic Chinese cohort

BMC Public Health, 2019
Background First-degree relatives of patients with diabetes (FDR) tend to have impaired insulin activity, which lead to the alternation of circulating cytokine levels.
Yiting Xu, Yun Shen, Xiaojing Ma, Chengchen Gu, Yufei Wang, Yuqian Bao   +5 more
doaj   +1 more source

Transcriptomic comparison of osteopontin, osteocalcin and core binding factor 1 genes between human adipose derived differentiated osteoblasts and native osteoblasts

Advanced Biomedical Research, 2012
Background: There are significant limitations in repair of irrecoverable bone defects. Stem-cell therapy is a promising approach for the construction of bone tissue.
Vahid Bahrambeigi, Rasoul Salehi, Batool Hashemibeni, Ebrahim Esfandiari   +3 more
doaj   +1 more source

Cytokines, Adipokines, and Bone Markers at Rest and in Response to Plyometric Exercise in Obese vs Normal Weight Adolescent Females

Frontiers in Endocrinology, 2020
BackgroundIn adults, excess adiposity has been associated with low-grade, chronic inflammation and compromised bone health, but less is known about these linkages in children.
Nigel Kurgan, Nigel Kurgan, Katherine McKee, Melissa Calleja, Andrea R. Josse, Andrea R. Josse, Panagiota Klentrou, Panagiota Klentrou   +7 more
doaj   +1 more source

New Insights into the Biology of Osteocalcin

Bone, 2015
Osteocalcin is among the most abundant proteins in bone and is produced exclusively by osteoblasts. Initially believed to be an inhibitor of bone mineralization, recent studies suggest a broader role for osteocalcin that extends to the regulation of ...
Meredith L Zoch, T. Clemens, Ryan C. Riddle   +2 more
semanticscholar   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source