Results 101 to 110 of about 43,856 (265)

Bone-Derived Extracellular Vesicles: Novel Players of Interorgan Crosstalk

open access: yesFrontiers in Endocrinology, 2019
An increasing number of studies have shown that bone plays an active role in regulating glucose metabolism, affects renal, and cardiovascular diseases and even influences the development of offspring. These novel findings have indicated that bone plays a
Yi Li   +8 more
doaj   +1 more source

Musculoskeletal Outcomes of Glucagon‐Like Peptide‐1 Receptor Agonists Versus Other Antiobesity Agents in Nondiabetic Adults

open access: yesObesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu   +5 more
wiley   +1 more source

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

open access: yesPediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu   +6 more
wiley   +1 more source

Effects of transcranial direct current stimulation on pain and function in patients with knee osteoarthritis: A systematic review and meta‐analysis

open access: yesPM&R, EarlyView.
Abstract Objective The aim of this systematic review and meta‐analysis is to determine the effects of transcranial direct current stimulation (TDCS) on pain (considering the different types of pain measured) and function in adults with knee osteoarthritis (OA).
Noemí Moreno‐Segura   +4 more
wiley   +1 more source

Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte

open access: yesPoultry Science
: Fatty liver hemorrhage syndrome (FLHS) is the leading cause of noninfectious mortality in caged layers worldwide. Osteocalcin (OCN) is a protein secreted by osteoblasts, and its undercarboxylated form (ucOCN) acts as a multifunctional hormone that ...
W.J. Tu   +5 more
doaj   +1 more source

The Effects of Early Postnatal Alcohol Exposure on Bone Molecular Composition in a Mouse Model. [PDF]

open access: yesAlcohol Clin Exp Res (Hoboken)
Early postnatal alcohol exposure was associated with long‐term changes in adult bone molecular composition and increased CTX‐I, indicating persistent effects on skeletal biology. Overlap with gavage‐related changes highlights the need to distinguish alcohol‐specific effects from procedural influences.
Dursun I, Elibol B, Ustaoglu SG.
europepmc   +2 more sources

Curcumin Alleviates the Osteogenesis Inhibition and the Aging Process in BMSCs Induced by Iron Overload Through Activating the NRF2/GPX4 Pathway

open access: yesPhytotherapy Research, EarlyView.
Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che   +7 more
wiley   +1 more source

Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications

open access: yesThe Chemical Record, EarlyView.
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer   +11 more
wiley   +1 more source

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