Results 221 to 230 of about 130,158 (334)

17β-Estradiol Antagonizes Effects of 1α,25-Dihydroxyvitamin D3 on Interleukin-6 Production and Osteoclast-Like Cell Formation in Mouse Bone Marrow Primary Cultures* [PDF]

, 1997
C Schiller, Reinhard Gruber, Kurt Redlich, Guan-Min Ho, F. Katzgraber, Martin Willheim, Peter Pietschmann, Meinrad Peterlik   +7 more
openalex   +1 more source

Biomaterials‐Involved Construction of Extracellular Matrices for Tumor Blockade Therapy

Exploration, EarlyView.
Extracellular matrices (ECMs) play a crucial role in tumor growth and metastases by providing structural support and facilitating tumor cell proliferation. In this review, we explore the development of artificial ECMs engineered through biomineralization, fibrogenesis, and gelation. These bioinspired ECMs create a protective barrier around tumor cells,
Jinfeng Sun, Yang Liu, Jingshan Sun, Jianxun Ding, Xuesi Chen   +4 more
wiley   +1 more source

Roles of JAK-STAT signaling and granulocyte-macrophage colony-stimulating factor in the development of osteitis and bone microstructure changes in rheumatoid arthritis. [PDF]

Arthritis Res Ther
Yoshida T, Murotani Y, Murata K, Imai H, Iwasaki T, Nakayama Y, Katsushima M, Shirakashi M, Nakashima R, Watanabe R, Murakami K, Yoshifuji H, Morinobu A, Hashimoto M.   +13 more
europepmc   +1 more source

Detection of estrogen receptor alpha, carbonic anhydrase II and tartrate-resistant acid phosphatase mRNAs in putative mononuclear osteoclast precursor cells of neonatal rats by fluorescence in situ hybridization [PDF]

, 1998
WH Huang, AT Lau, LL Daniels, Hiroshi Fujii, Ulrich Seydel, DJ Wood, JM Papadimitriou, Minghao Zheng   +7 more
openalex   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Dusp1 in osteolytic diseases-mechanisms and therapeutic potential. [PDF]

Sci Rep
Liu B, Lei M, Wan B, Feng Y, Teng Y, Xi D, Chen S, Zeng G, Zong S.   +8 more
europepmc   +1 more source

The Heart and the Osteoclasts

Cardiology, 2013
openaire   +3 more sources

Suppression of TRPV5 Regulates Microglia‐Mediated Neuroinflammation Following Status Epilepticus

Glia, EarlyView.
TRPV5 is involved in microglial activation following epileptic seizures. TRPV5 upregulation in microglia drives neuroinflammation. TRPV5 inhibition by econazole reduces neuroinflammation via suppressing AKT/NF‐κB/NLRP3 signaling cascade. ABSTRACT Neuroinflammation, predominantly associated with glial activation and the release of various inflammatory ...
Soojin Park, Se Hoon Kim, Chul Hoon Kim, Kyoung Hoon Jeong, Won‐Joo Kim   +4 more
wiley   +1 more source

CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation via NSUN5-mediated m5C modification. [PDF]

Sci Rep
Deng Z, Zhong W.
europepmc   +1 more source

Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis [PDF]

, 2018
Bukowska-Straková, Karolina, Dulak, Józef, Florczyk-Soluch, Urszula, Józefczuk, Ewelina, Józkowicz, Alicja, Mendel, Mateusz, Nowak, Witold, Stępniewski, Jacek, Viscardi, Monika   +8 more
core   +1 more source