Results 291 to 300 of about 182,622 (382)

The role of active constituents of in traditional Chinese medicine for primary osteoporosis: a mechanistic review. [PDF]

Front Endocrinol (Lausanne)
Song C, Zeng L, Zhao C.
europepmc   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

ANXA2 Regulates RANKL-Induced Osteoclast Differentiation Through STAT3 Signaling in Breast Cancer. [PDF]

Breast Cancer (Dove Med Press)
Yuan J, Xin F, Wang R.
europepmc   +1 more source

Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

Journal of Bone and Mineral Research, 2016
Megan M. Weivoda, M. Ruan, Christine M. Hachfeld, Larry Pederson, A. Howe, R. Davey, J. Zajac, Yasuhiro Kobayashi, B. Williams, J. Westendorf, S. Khosla, M. Oursler   +11 more
semanticscholar   +1 more source

The Nutritional Composition and Multi‐Omics Analysis of Raw Milk From Normande and Holstein Cows

Food Frontiers, EarlyView.
Normande milk is characterized by high protein and fat content, whereas Holstein milk is distinguished by its high milk yield. However, few studies have reported on their compositional differences. Thus, we used physicochemical and multi‐omics techniques to investigate the compositional differences between Normande and Holstein raw milks. ABSTRACT Milk
Yuanyuan Li, Haifu Jia, Yaping Zheng, Xiaoxia Sun, Yaqian Zhang, Wei Liu, Wei Zhang, Yujun Jiang, Qianyu Zhao, Ling Guo   +9 more
wiley   +1 more source

Osteocytes Produces RANKL Via Wnt-TGFβ Signaling Axis for Osteoclastogenesis. [PDF]

Int J Biol Sci
Liu Y, Zhao L, Li M, Gong W, Wang X, Cheng Y, Zhang Y, Wang P, Luo Y, Zhang Y, Shao Y, Taketo MM, Bellido T, Shao G, Liu X, Tu X.   +15 more
europepmc   +1 more source

The role of osteoclast differentiation and function in skeletal homeostasis.

Journal of Biochemistry (Tokyo), 2016
K. Ikeda, S. Takeshita
semanticscholar   +1 more source

Mimicking DOUGONG brackets orchestrate regulating inflammation and mechanical stimuli for osteochondral regeneration using 3D printing

Interdisciplinary Medicine, EarlyView.
Akermanite scaffolds promote osteogenic differentiation of BMSCs through regulating the PI3K/Akt signaling pathway, and strontium ions enhance the akermanite effects by mediating the cytokine‐cytokine receptor interaction pathway. Thus, the enhancements of osteogenesis in subchondral bone coupled with the chondral‐promoting effects of chondrocytes ...
Bo Li, Yaqi Zhang, Xuerui Zhou, Weiguo Wang, Fan Yang, Qiushi Wei, Leilei Chen, Ziqi Li, Mincong He, Xiaoming He, Shengting Chai, Xiuhong Cao, Rui Wang, Tongmeng Jiang, Chen Wang, Wei He   +15 more
wiley   +1 more source

ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts. [PDF]

J Biol Chem
Jentschel L, Blangy A, Bompard G.
europepmc   +1 more source

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

The Journal of Clinical Pharmacology, EarlyView.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado, Erika N. Scott, Shahrad R. Rassekh, Catrina M. Loucks, Wan‐Chun Chang, Edward J. Raack, Jessica N. Trueman, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety Consortium   +9 more
wiley   +1 more source