Phloridzin Mitigates Gorham-Stout Disease by Dual Inhibition of Osteoclastogenesis Related to the Ca<sup>2+</sup> Signaling Pathway and Vascular Proliferation. [PDF]
ACS OmegaTrang NM, Kim EN, Jeong GS.
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iTr35 cells: a novel immunoregulatory subset involved in bone loss in rheumatoid arthritis and clinical implications. [PDF]
Ann MedLi Y, An M, Yao L, Lu J.
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Licochalcone D inhibits osteoclast differentiation and postmenopausal osteoporosis by inactivating the NF-κB signaling pathway. [PDF]
J Orthop Surg ResShen X +7 more
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Letter to the editor regarding 'iTr35 cells: a novel immunoregulatory subset involved in bone loss in rheumatoid arthritis and clinical implications'. [PDF]
Ann MedLi LM, Lv SC.
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Hydrothermal Magnesium Alloy Extracts Modulate MicroRNA Expression in RAW264.7 Cells: Implications for Bone Remodeling. [PDF]
J Funct BiomaterCosta V +10 more
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The origin of the osteoclast remains controversial even though investigations using light microscopy, tissue culture, electron microscopy, microcinematography, autoradiography, parabiosis, quail chick nuclear markers, giant lysosomal markers in beige mice, Y chromosomes, bone marrow cell culture, and monoclonal antibodies have been performed since its ...
Hiroo Yabe, Hiroshi Bun, Hideya Hanaoka
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The mechanism by which bone collagen and other organic components are degraded by the osteoclast during osteoclastic bone resorption was unclear until the 1980s. Studies conducted since the early 1990s have identified lysosomal proteases, mainly cathepsins that are active at low pH, involved in osteoclastic bone resorption.
Teruo Tanaka +2 more
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It is now dogma that osteoclasts (OCs) arise from cells of the monocyte/macrophage lineage. However, data are accumulating suggesting that a relationship exists between B lymphocytes (B cells) and OC differentiation. Although the exact nature of this relation is unknown, it takes at least two forms.
Mark C. Horowitz, Joseph A. Lorenzo
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Transfection of Osteoclasts and Osteoclast Precursors
2011Osteoclasts and their precursors have traditionally been considered difficult cells to transfect using standard approaches. Here, we describe several methods for transfection of mature osteoclasts and their precursors using the Amaxa™ Nucleofector system, lentiviruses, and adenoviruses.
David Mellis +2 more
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