Results 251 to 260 of about 132,120 (348)

Wilforine attenuates inflammatory osteolysis by suppressing osteoclast fusion through JAK-STAT-stomatin immunoregulatory signaling. [PDF]

Front Immunol
Geng S, Guan Y, Ye Z, Zhao D, Jiang Y, Fu J, Sheng H, Yang S, Liu H, Deng F, Yu S, Yimingjiang M, Wu Y, Li C, Huang G.   +14 more
europepmc   +1 more source

Effects of Rankl and M-Csf on Osteoclast Differentiation in Raw264.7 Cells

Zeyu Xie, Yingzhen Lai, Yuerong Gao, Hong Wang, YanYin Lin, Yi Wu, Ge Yin, Xinze Weng, Yan Chen   +8 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

The therapeutic potential of descending regulatory pathways from brain to bone in osteoporosis: focusing on the brain-bone axis. [PDF]

Front Endocrinol (Lausanne)
Rong Y, Zhang L, Xu M, Chen Y, Wang X, Li S, Yang G, Chen G.   +7 more
europepmc   +1 more source

Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas: a narrative review [PDF]

Hao‐Xiang Wu
openalex   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Neural regulation of bone: from central neural circuits to peripheral innervation of the skeletal stem cell niche. [PDF]

Bone Res
Chen Z, Luo Z, Greenblatt MB, Wu Z, Xu R.   +4 more
europepmc   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Fibroblast-derived NEU1 as a therapeutic target for improving cortical bone integrity and fracture healing. [PDF]

Theranostics
Wu Y, Ai H, Zhang C, Qu Y, Tan J, Limjunyawong N, Xu J, Dong S, Luo F, Dou C.   +9 more
europepmc   +1 more source