Results 121 to 130 of about 90,541 (292)

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

FasL induces expression of Mmp13 and Osterix in bone cells

open access: yesBone Reports, 2021
Adéla Kratochvílová   +4 more
doaj  

New Insights into the Molecular Pathology of Osteogenesis Imperfecta [PDF]

open access: bronze, 1989
W G Cole   +2 more
openalex   +1 more source

PRMT3‐Mediated H4R3me2a Promotes Primary Age‐Related Tauopathy by Driving Tau Hyperphosphorylation in Neuron

open access: yesAdvanced Science, EarlyView.
This study identifies PRMT3‐mediated H4R3me2a as a critical driver of tau hyperphosphorylation in primary age‐related tauopathy. Mechanistic insights reveal that the PRMT3/H4R3me2a/miR‐448 axis suppresses IGF1R expression via epigenetic regulation, further dysregulating the PI3K/AKT/GSK3β pathway.
Haotian Liu   +9 more
wiley   +1 more source

Osteogenesis Imperfecta [PDF]

open access: yesEar, Nose & Throat Journal, 2000
Dawson, Paul A., Marini, Joan C.
openaire   +4 more sources

Volumetric Engineered 3D Drug Reservoir Against Diabetic Implant Infection via Cuproptosis‐Like Bacterial Death and Hunger‐Triggered Maintenance of Mitochondrial Integrity

open access: yesAdvanced Science, EarlyView.
This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li   +8 more
wiley   +1 more source

Analysis of cell cycle related gene expression in Myb deficient mandible – a pilot study

open access: yesBone Reports, 2021
Sabina Stouracova   +5 more
doaj  

Cardiovascular involvement in osteogenesis imperfecta. [PDF]

open access: bronze, 1986
John Hortop   +4 more
openalex   +1 more source

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