Results 131 to 140 of about 165,191 (338)

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Distraction Osteogenesis in Dentistry

, 2010
Distraction osteogenesis is a technique for induction of new bone formation between two segments of a bone that presents wide possibilities of use in Dentistry. However, the available information on this subject is still scarce.
BEZZON, Osvaldo Luiz, FERNANDES, Flavio Henrique Carrico N., ORSI, Iara Augusta   +2 more
core  

Analysis of cell cycle related gene expression in Myb deficient mandible – a pilot study

Bone Reports, 2021
Sabina Stouracova, Eva Matalova, Jon Frampton, Mary Clarke, Premysl Bartos, Veronika Oralova   +5 more
doaj   +1 more source

Hierarchical Nanoplatform Integrating Oxidative–Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy

Advanced Science, EarlyView.
A hierarchical CM/LDH nanoplatform integrates ROS‐scavenging Ce‐MOF nanozymes with acid‐neutralizing CaAl‐LDH and is delivered within GelMA hydrogel to diabetic bone defects. By remodeling the oxidative‐acidic microenvironment, preserving mitochondrial homeostasis, and suppressing mtDNA–cGAS–STING inflammatory signaling, CM/LDH reduces proinflammatory ...
Xu Chen, Xingyu Zhu, Zhixin Qiu, Yijia Zhu, Xinhui Zheng, Dongqi Fan, Jinglei Zhan, Congxiu Mao, Ping Ji, Tao Chen, Qingqing He   +10 more
wiley   +1 more source

Screening of osteogenesis related gene expression in caspase-8 deficient MC3T3-E1 cells

Bone Reports, 2021
Barbora Vesela, Adela Kratochvilova, Kamila Rihova, Filip Trcka, Petr Benes, Eva Matalova   +5 more
doaj   +1 more source

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

Successful re-distraction osteogenesis on the consolidated bone resulted from previous distraction osteogenesis of tibia: A case report

Trauma Case Reports
Treating massive tibial bone defects resulting from high-energy trauma are pose a significant challenge in the field of orthopaedic surgery. While several methods exist for addressing extensive bone defects, distraction osteogenesis (DO) recognized as ...
Asep Santoso, Seti Aji Hadinoto, Hillan Akbar, Dykall Naf'an Dzikri   +3 more
doaj   +1 more source

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

Advanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen, Jianhua Lv, Yuanqing Cai, Xuhui Yuan, Hongxin Hu, Jiayu Li, Yiming Lin, Hongyan Li, Lan Lin, Huangfeng Lin, Chaofan Zhang, Qijin Wang, Ying Huang, Zida Huang, Wenbo Li, Susheng Niu, Jianhua Lin, Bin Yang, Xinyu Fang, Wenming Zhang   +19 more
wiley   +1 more source

Impact of Myb deficiency on Rank-Rankl-Opg signalling pathway in osteogenesis

Bone Reports, 2021
Veronika Oralová, Sabina Stouracova, Jon Frampton, Mary Clarke, Premysl Bartos, Eva Matalova   +5 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source