Results 151 to 160 of about 145,083 (306)

A Doxorubicin‐Loaded Liposomes Baghdadite System for Localized Osteosarcoma Therapy and Bone Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam   +8 more
wiley   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi   +2 more
wiley   +1 more source

Growth dynamics, skeletochronology, and histovariability of the theropod dinosaur Berthasaura leopoldinae

open access: yesThe Anatomical Record, EarlyView.
Osteohistological sampling on different bones of theropod dinosaur documents discrepant age record, growth, and metabolism. This could result unprecise paleobiological inferences if samplings are based on single bones. However, multi‐bone sampling can attenuate these discrepancies, helping to infer growth dynamics and physiology of these extinct ...
Geovane Alves de Souza   +3 more
wiley   +1 more source

Osteogenesis Imperfecta [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1916
openaire   +2 more sources

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

open access: yesThe Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore   +5 more
wiley   +1 more source

Osteohistology of two phorusrhacids reveals uninterrupted growth strategy

open access: yesThe Anatomical Record, EarlyView.
Abstract Phorusrhacidae were apex predators that primarily dominated South America ecosystems for at least 40 million years with their imposing size and predatory lifestyle—yet some aspects of their biology remain poorly understood. Osteohistology is a tool for understanding growth dynamics and biomechanical adaptations.
Lotta Dreyer   +2 more
wiley   +1 more source

High Return to Activity and Low Rerupture Rates Following All‐Inside Quadriceps Tendon Anterior Cruciate Ligament Reconstruction With Bone Marrow Aspirate, Demineralized Bone Matrix, and Suture Tape Augmentation

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate clinical outcomes of anterior cruciate ligament reconstruction (ACLR) using a quadriceps tendon autograft (QTA) with adjunctive bone marrow aspirate concentrate, demineralized bone matrix, and suture tape augmentation. Methods A retrospective review was conducted using a prospectively maintained registry of patients who underwent ...
Jake Peterson   +8 more
wiley   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat   +14 more
wiley   +1 more source

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