ABSTRACT Objective To evaluate the effects of antimicrobial photodynamic therapy (aPDT), systemic pharmacological therapy, and their combination on irradiated mandibular post‐extraction bone repair relevant to osteoradionecrosis (ORN) development in a rat model. Methods Twenty‐six male Wistar rats were initially randomized into five experimental groups:
Larissa Lopes Fonseca +9 more
wiley +1 more source
Cyclic distraction-compression promotes bone regeneration during distraction osteogenesis through the Piezo1-YAP-β-catenin axis. [PDF]
Tang L +11 more
europepmc +1 more source
ABSTRACT In this study, 15MgHAp (xMg = 0.15) was synthesized by an adapted method, lyophilized, and characterized to evaluate its physicochemical and biological properties. The ultrasound measurements (US) evaluated the stability of the resulting MgHAp gel. Complementary surface information was obtained using a scanning ultrasonic microscope (SUM). The
Liliana Ghegoiu +7 more
wiley +1 more source
Correction: Li et al. Multifunctional Fe<sub>3</sub>O<sub>4</sub>@ZIF-8 Nanoparticles with Antibiosis and Osteogenesis for Treatment of Jaw Osteomyelitis. <i>Pharmaceutics</i> 2026, <i>18</i>, 359. [PDF]
Li H +13 more
europepmc +1 more source
Recent Advances in Cryogel Applications for Musculoskeleatal Regeneration
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim +4 more
wiley +1 more source
E3 ubiquitin ligases in bone homeostasis: from regulatory mechanisms to skeletal diseases and therapeutic targeting. [PDF]
Zhao Y, Cao N, Yang W, Wang Y, Wang W.
europepmc +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Correction: Visible-light-triggered BMP-2 release from enzymatically crosslinked marine collagen-alginate hydrogel blends enhances osteogenesis in dental pulp stem cells. [PDF]
Torelli F.
europepmc +1 more source
ABSTRACT Objective To investigate the additional clinical value of nuchal translucency (NT) measurement at the first‐trimester anomaly scan (FTAS) in a setting with first‐tier non‐invasive prenatal testing (NIPT). Method This nationwide prospective cohort study, part of the IMITAS study on FTAS implementation, included all pregnancies with increased NT
Eline E. R. Lust +15 more
wiley +1 more source
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source

