BMSC-Derived Exosomal miR-29a Promotes Angiogenesis and Osteogenesis
Frontiers in Cell and Developmental Biology, 2020 Angiogenesis and osteogenesis are tightly coupled during bone modeling and remodeling processes. Here we reported that bone marrow mesenchymal stem cell (BMSC)-derived exosomal miR-29a promotes angiogenesis and osteogenesis in vitro and in vivo.
Guo-Dong Lu +3 more
semanticscholar +1 more source
Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model. [PDF]
, 2014 The clinical management of bone defects caused by trauma or nonunion fractures remains a challenge in orthopedic practice due to the poor integration and biocompatibility properties of the scaffold or implant material. In the current work, the osteogenic
Barrientos-Durán, Antonio +5 more
core +2 more sources
Pan African Medical Journal, 2021 Osteogenesis imperfecta is a rare hereditary connective tissue disorder that affects the bones fragility. It causes the bones to break easily. The defective gene affects the body mechanism to form collagen, which strengthens the bone. A 20-year-old male patient came with complaints of pain in the left leg since morning.
Surya Besant Natarajan +1 more
openaire +3 more sources
Frontiers in Cell and Developmental Biology, 2021 Osteogenesis imperfecta is a genetic disorder disrupting bone development and remodeling. The primary causes of osteogenesis imperfecta are pathogenic variants of collagen and collagen processing genes.
Christopher L. Schwebach +2 more
doaj +1 more source
Cephalometric studies of the mandible, its masticatory muscles and vasculature of growing Göttingen Minipigs — A comparative anatomical study to refine experimental mandibular surgery [PDF]
, 2019 Over many decades, the Göttingen Minipig has been used as a large animal model in experimental surgical research of the mandible. Recently several authors have raised concerns over the use of the Göttingen Minipig in this research area, observing ...
Corte, Guiliano Mario +4 more
core +3 more sources
Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome [PDF]
, 2013 Background: Whereas mutations affecting the helical domain of type I procollagen classically cause Osteogenesis Imperfecta (OI), helical mutations near the amino (N)-proteinase cleavage site have been suggested to result in a mixed OI/Ehlers-Danlos ...
De Paepe, Anne +9 more
core +2 more sources
Evaluation of MC3T3-E1 Cell Osteogenesis in Different Cell Culture Media
International Journal of Molecular Sciences, 2021 Many biomaterials have been evaluated using cultured cells. In particular, osteoblast-like cells are often used to evaluate the osteocompatibility, hard-tissue-regeneration, osteoconductive, and osteoinductive characteristics of biomaterials.
Makoto Izumiya +10 more
semanticscholar +1 more source
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
core +2 more sources
Cell communication and relevant signaling pathways in osteogenesis–angiogenesis coupling
Bone ResearchOsteogenesis is the process of bone formation mediated by the osteoblasts, participating in various bone-related physiological processes including bone development, bone homeostasis and fracture healing. It exhibits temporal and spatial interconnectivity
Shuqing Li +6 more
semanticscholar +1 more source
Osteomodulin positively regulates osteogenesis through interaction with BMP2
Cell Death and Disease, 2021 Osteomodulin (OMD), a member of the small leucine-rich proteoglycan family, distributes in mineralized tissues and is positively regulated by bone morphogenetic protein 2 (BMP2).
Wen-zhen Lin +5 more
semanticscholar +1 more source