Results 141 to 150 of about 5,237 (179)
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In Vitro Osteoinduction of Demineralized Bone
Artificial Cells, Blood Substitutes, and Biotechnology, 1998Among numerous available materials for osseous repair and reconstruction, those presenting osteoinductive characteristics and promoting bone regeneration are preferable. Fresh autologous bone is one of the most effective, but it has some disadvantages and risks.
P, Torricelli +3 more
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Journal of Dental Research, 1996
Freeze-dried Saos-2, human osteosarcoma cells, and extracts of Saos-2 cells contain all components necessary to induce ectopic new bone and marrow when implanted into athymic Nu/Nu nuce. On the other hand, human osteosarcoma cells of the U-2 OS strain failed to induce bone formation under the same experimental conditions.
P, Raval +6 more
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Freeze-dried Saos-2, human osteosarcoma cells, and extracts of Saos-2 cells contain all components necessary to induce ectopic new bone and marrow when implanted into athymic Nu/Nu nuce. On the other hand, human osteosarcoma cells of the U-2 OS strain failed to induce bone formation under the same experimental conditions.
P, Raval +6 more
openaire +2 more sources
Materialwissenschaft und Werkstofftechnik, 2004
AbstractBone grafting is a widely used procedure to treat bone defects. Various synthetic bone substitutes are gaining upon autologous cancellous bone, which is still the most effective graft material, despite the associated morbidity at the harvesting site.
T. Stoll +3 more
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AbstractBone grafting is a widely used procedure to treat bone defects. Various synthetic bone substitutes are gaining upon autologous cancellous bone, which is still the most effective graft material, despite the associated morbidity at the harvesting site.
T. Stoll +3 more
openaire +1 more source
Osteoinduction of porous bioactive titanium metal
Biomaterials, 2004This is the first report of bone induction in a non-osseous site by titanium metal, which has long been recognized as a non-bioactive material. After undergoing specific chemical and thermal treatments, porous bioactive titanium induced bone formation without the need of additional osteogenic cells or osteoinductive agents.
Masashi Neo
exaly +3 more sources
A Rationale for Delivery of Osteoinductive Proteins
Tissue Engineering, 1996Highly pure, recombinant human osteoinductive proteins make it possible to consider programmable osteoneogenesis. Until recently, it was believed that a bioresorbable excipient or physiologic solution would suffice to transport osteoinductive agents from source to wound.
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Mechanisms of Osteoinduction/Chondroinduction by Demineralized Bone
Journal of Craniofacial Surgery, 2009Demineralized bone is widely used for osseous reconstructive procedures. Bone morphogenetic proteins (BMPs) have been studied as the putative active components of demineralized bone; recombinant BMPs are Food and Drug Administration-approved for use with scaffold carriers.
Julie, Glowacki +2 more
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Osteoinductive and Osteoconductive Biomaterials
2020With combinatorial approaches getting stronger to design materials with better functionalities and compatibility for restoring bone tissue, it is becoming important to understand the progress and evolution of existing and newly designed materials. For being clinically usable, they should have features that address the biomechanical, biochemical, and ...
Shreya Agrawal, Rohit Srivastava
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The Osteoinductivity of Silicate-Substituted Calcium Phosphate
Journal of Bone and Joint Surgery, 2011The osteoinductivity of silicate-substituted calcium phosphate and stoichiometric calcium phosphate was investigated with use of ectopic implantation. Implants with a macroporosity of 80% and a strut porosity of 30% were inserted into sites located in the left and right paraspinal muscles of six female sheep.After twelve weeks in vivo, a longitudinal ...
Melanie J, Coathup +5 more
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Osteoinductive hydroxyapatite-coated titanium implants
Biomaterials, 2012Previous studies have shown that heterotopic induction of bone formation by calcium phosphate-based macroporous constructs is set into motion by the geometry of the implanted substrata, i.e. a sequence of repetitive concavities assembled within the macroporous spaces.
Ugo, Ripamonti +2 more
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Osteoinductive Ability of Human Allograft Formulations
Journal of Periodontology, 2006Background: Bone graft materials are needed in periodontics that are osteoinductive, have good handling characteristics, and have physical properties that provide appropriate stiffness for the treatment site. Demineralized freeze‐dried bone allograft (DFDBA), also called demineralized bone matrix (DBM), is osteoinductive but requires a carrier to meet ...
Barbara D, Boyan +5 more
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