Transcriptomic insights into nerve growth factor–associated appositional bone formation in the reparative zone in osteonecrosis of the femoral head [PDF]
Journal of Orthopaedic Surgery and ResearchBackground In osteonecrosis of the femoral head, appositional bone formation occurs in the reparative zone, where new trabeculae surround necrotic bone, leading to trabecular thickening. However, the underlying molecular mechanisms remain unclear.
Yusuke Ayabe +6 more
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Recent advances of DNA methylation in osteonecrosis of the femoral head [PDF]
Frontiers in GeneticsDNA methylation, maintenance, and demethylation are essential for maintaining normal physiological functions. Recent studies have revealed that DNA methylation plays a crucial role in the progression of osteonecrosis of the femoral head.
Tingting Zhou +7 more
doaj +2 more sources
GDF11 alleviates glucocorticoid-induced osteonecrosis of the femoral head by regulating angiogenesis via the PI3K-AKT-eNOS pathway [PDF]
Communications BiologyGlucocorticoid-induced osteonecrosis of the femoral head is a joint dysfunction disease. Impaired local angiogenesis and reduced perfusion are early pathological features of glucocorticoid-induced osteonecrosis of the femoral head, resulting from ...
Zhicheng Liu +14 more
doaj +2 more sources
Human Immunodeficiency Virus in the Focus of Bone Tissue Destruction in Patients With Aseptic Osteonecrosis of the Femoral Head: Two Case Reports [PDF]
Travmatologiâ i Ortopediâ Rossii, 2023 Background. Osteonecrosis of the femoral head is significantly more common in HIV-positive patients than in the general population. The etiology and pathogenesis of this process are not fully understood.
Evgeny O. Peretsmanas +4 more
doaj +1 more source
Early results of cementless hip arthroplasty in the treatment of femoral head posttraumatic and atraumatic osteonecrosis [PDF]
Vojnosanitetski Pregled, 2005 Aim. To evaluate the value of cementless hip arthroplasty in the treatment of posttraumatic and atraumatic osteonecrosis (ON) of the femoral head. Methods.
Jeremić Dragan +3 more
doaj +1 more source
AVASCULAR NECROSIS OF THE FEMORAL HEAD AFTER COVID-19: A CASE REPORT
Anti-Aging Eastern Europe, 2023 Avascular necrosis of the femoral head can traumatic or non-traumatic in origin. Embolism (hemoglobinopathies, dysbaric osteonecrosis), corticosteroid treatment, alcohol usage, pelvic irradiation, and genetic susceptibility are among the causes of this ...
Ilke Coskun Benlidayi +2 more
doaj +1 more source
Susceptibility of Males, but Not Females to Developing Femoral Head Osteonecrosis in Response to Alcohol Consumption. [PDF]
PLoS ONE, 2016 We previously reported that ethanol-containing liquid diet feeding induces osteonecrosis of the femoral head in male rats. Also, it was reported that a large amount of consumed ethanol and a long-term history of drinking were risk factors for ...
Junya Shimizu +8 more
doaj +1 more source
Frontiers in Physiology, 2018 Aims: The purpose of this study was to assess the relationship between genetic variants and steroid-induced osteonecrosis of the femoral head (SONFH) in steroid use populations.Methods: We searched the public databases up to April 15, 2018.
Xiantao Chen +5 more
doaj +1 more source
Simultaneous Bilateral Femoral Osteonecrosis in Gaucher Disease
Life, 2023 Gaucher disease (GD) is one of the most common lysosomal storage disorders. Bone complications are the most critical irreversible consequence of GD.
Daniel Cohen +5 more
doaj +1 more source
Treatment of osteonecrosis of the femoral head using autologous cultured osteoblasts: a case report
Journal of Medical Case Reports, 2008 Introduction Osteonecrosis of the femoral head is a progressive disease that leads to femoral head collapse and osteoarthritis. Our goal in treating osteonecrosis is to preserve, not to replace, the femoral head.
Kim Seok-Jung +4 more
doaj +1 more source