Results 51 to 60 of about 21,214 (278)

Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SIONFH) is a debilitating orthopedic condition. This study investigated the mechanism of Tanshinone I (TsI) in SIONFH modulating apoptosis in SIONFH via the PI3K/AKT/mTOR pathway. A SIONFH rat model was treated with TsI and a PI3K activator. Bone mineral density (BMD), bone volume/total volume
Qing Su, Jia Chen
wiley   +1 more source

Pigmented Villonodular Synovitis Causing Osteonecrosis of the Femoral Head: A Case Report

Case Reports in Orthopedics, 2013
We report a case of a 27-year-old man with pigmented villonodular synovitis of the hip joint with coincident osteonecrosis of the femoral head. According to our review of the English-language literature, no detailed report of osteonecrosis of the femoral
Tomohiro Mimura, Taku Kawasaki, Keitaro Yagi, Kanji Mori, Shinji Imai, Yoshitaka Matsusue   +5 more
doaj   +1 more source

Effects of angiotensin II combined with asparaginase and dexamethasone on the femoral head in mice: A model of steroid-induced femoral head osteonecrosis

Frontiers in Cell and Developmental Biology, 2022
Background: To study the pathogenesis of steroid-induced femoral head osteonecrosis, an ideal animal model is very important. As experimental animals, mice are beneficial for studying the pathogenesis of disease.
Jiahe Liu, Chenzhi Li, Fan Yang, Fan Yang, Minde Li, Baolin Wu, Haojie Chen, Shaopeng Li, Xiuzhi Zhang, Jiahui Yang, Yan Xia, Mingjian Wu, Yancheng Li, Baoyi Liu, Dewei Zhao   +14 more
doaj   +1 more source

Posterior femoral condylar morphology following mechanical vs. kinematic alignment using a medial‐pivot implant designed for mechanical alignment: A CT‐based comparative study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The kinematic alignment (KA) technique aims to restore native joint anatomy; however, the extent to which it restores posterior femoral condylar morphology after total knee arthroplasty (TKA) remains unclear. The posterior longitudinal overhang in the femoral condyle (PLOF) has been reported to affect clinical outcomes.
Yohei Ohyama, Yukihide Minoda, Sho Masuda, Ryo Sugama, Hideki Ueyama, Hidetomi Terai   +5 more
wiley   +1 more source

Qualitative and quantitative morphological indices of damage and reparation in idiopathic femoral head osteonecrosis in adults

Patologìâ, 2014
Aim. Idiopathic aseptic femoral head osteonecrosis is one of the diseases which happen often and in most cases lead to permanent disability. Methods and results.
V. V. Hryhorovskyi, О. E. Nirshberg
doaj   +1 more source

Three-dimensional distribution of cystic lesions in osteonecrosis of the femoral head

Journal of Orthopaedic Translation, 2020
Purpose: The aim of this study was to investigate the location characteristics of cystic lesions in a three-dimensional context and discuss the mechanism of formation.
Guang-Bo Liu, Rui Li, Qiang Lu, Hai-Yang Ma, Yu-Xuan Zhang, Qi Quan, Xue-Zhen Liang, Jiang Peng, Shi-Bi Lu   +8 more
doaj   +1 more source

Hypoxia-inducible factor prolyl hydroxylase inhibitor prevents steroid-associated osteonecrosis of the femoral head in rabbits by promoting angiogenesis and inhibiting apoptosis. [PDF]

PLoS ONE, 2014
The purpose of this study was to investigate the preventive effect of ethyl 3,4-dihydroxybenzoate(EDHB) on steroid-associated femoral head osteonecrosis(ONFH) in a rabbit model.
Lihong Fan, Jia Li, Zefeng Yu, Xiaoqian Dang, Kunzheng Wang   +4 more
doaj   +1 more source

Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg-Calvé-Perthes’ disease [PDF]

, 2016
Legg-Calvé-Perthes' (Perthes') disease is a developmental disease of the hip joint that may result in numerous short and long term problems. The etiology of the disease remains largely unknown, but the mechanism is believed to be vascular and/or ...
Acheson, Acheson, Adler, Allen, Anderson, Arie, Atsumi, Bahmanyar, Barker, Beals, Berg, Bergmann, Bergmann, Bergmann, Bohr, Brown, Bull, Burwell, Burwell, Caffey, Calvé, Camargo, Cameron, Canavese, Cannon, Catterall, Catterall, Choo, Chung, Churchill, Coyle, Crock, Currey, Danforth, Delclaux, Dillman, Donohue, Douglass, Duff, Ebong, Eckerwall, Edvardsen, Eijer, Eijer, Emr, Ezoe, Faraj, Fisher, García Mata, Gaskin, Gautier, Girdany, Goff, Gordon, Gray, Grzegorzewski, Guembecker, Güngör, Hailer, Hall, Hall, Hall, Hall, Hall, Hall, Harrison, Harrison, Harrison, Herndon, Herring, Herring, Hirano, Hofstaetter, Hong, Inoue, Isaac, Iwasaki, Joseph, Joseph, Joseph, Joseph, Kallio, Kamegaya, Kandzierski, Kataoka, Katz, Katz, Kawahara, Kawahara, Kealey, Kealey, Kemp, Kenet, Kim, Kim, Kim, Kim, Kitoh, Koob, Kristmundsdottir, Kristmundsdottir, Kristmundsdottir, Krul, Lappin, Laron, Larson, Lauritzen, Lee, Legg, Ljunggren, Lloyd-Roberts, Loder, Loder, Lubovsky, Madan, Margetts, McQuade, Mickelson, Moberg, Molloy, Moseley, Moulton, Nelitz, O'Higgins, Ogden, Osman, Osorio, Park, Perry, Perry, Perry, Perry, Perry, Perry, Perry, Perry, Perry, Perthes, Pillai, Pringle, Purry, Rab, Ralston, Rao, Rayfield, Rayner, Reynolds, Richmond, Rowe, Ruff, Salmaso, Salmingo, Salter, Sankar, Sharma, Shore, Smedley, Smith, Stuart, Stulberg, Suehiro, Suehiro, Tanner, Tardieu, Tardieu, Terjesen, Thompson, Thompson, Théron, Tomita, Toogood, Trueta, Tucker, Tutt, Ueo, Upadhyay, Upadhyay, Vasseur, Vaverka, Vila-Verde, Vosmaer, Wang, Weiner, Wiig, Wiig, Wijesekera, Winkleby, Wright, Wynne-Davies, Yoshida, Zarco, Zhang   +191 more
core   +1 more source

Research Progress of Tonifying Kidney and Promoting Blood Circulation in the Treatment of Steroid-induced Necrosis of Femoral Head [PDF]

, 2022
Osteonecrosis of the femoral head is a common disability disease of the hip joint in China, and osteonecrosis of the femoral head caused by hormone factors is the most common, which is related to the gradual increase in the utilization rate of ...
Li, Yanmin, Li, Yingang, Wang, Yongcai
core   +1 more source

Follow‐up of osteonecrosis in paediatric acute lymphoblastic leukaemia patients treated with the NOPHO ALL2008 protocol

British Journal of Haematology, EarlyView.
Summary Although osteonecrosis (ON) is a common sequel after childhood acute lymphoblastic leukaemia treatment and may cause debilitating symptoms, its prognosis remains underexplored. We describe the radiological evolution of ON lesions in a Finnish patient cohort treated according to the The Nordic Society of Paediatric Haematology and Oncology ...
Roosa Rokkanen, Henri Aarnivala, Sanna Huhtaniska, Sauli Palmu, Tytti Pokka, Tuuli Pöyhönen, Maria Suo‐Palosaari, Pauliina Utriainen, Liisa Järvelä, Riitta Niinimäki   +9 more
wiley   +1 more source