Results 81 to 90 of about 178,708,228 (184)

Sequential Anabolic and Antiresorptive Treatment Promotes Medication‐Related Osteonecrosis of the Jaw in Mice

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To investigate the effects of sequential administration of romosozumab and denosumab on post‐extraction socket healing and osteonecrosis development in a murine tooth extraction model. Methods Forty female mice were randomly assigned to four groups: control (Ctrl), romosozumab (Rm), denosumab (Dmab), and sequential romosozumab ...
Seo‐Yeong An   +3 more
wiley   +1 more source

Platelet Rich Plasma in the Treatment of Bisphosphonate-Related Osteonecrosis of the Jaw: Personal Experience and Review of the Literature

open access: yesInternational Journal of Dentistry, 2014
Bisphosphonates (BPs) are a class of synthetic drugs commonly used to treat bone metastasis and various bone diseases that cause osseous fragility (such as osteoporosis). Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a common complication in
F. Longo   +6 more
doaj   +1 more source

Algorithm for Surgical Management in Patients in Treatment With Medication Associated With Osteonecrosis of the Jaws

open access: yesOral Surgery, EarlyView.
ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra   +3 more
wiley   +1 more source

Refractory healing after surgical therapy of osteonecrosis of the jaw: associated risk factors in aged patients

open access: yes, 2019
Ji-Youn Kim,1 Hyun Chul Song,1 Hyeon-Gun Jee21Division of Oral & Maxillofacial Surgery, Department of Dentistry, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; 2Healthcare Innovation ...
Jee HG, Kim JY, Song HC
core  

Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

open access: yesOrthopaedic Surgery, EarlyView.
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Xiang Yao   +7 more
wiley   +1 more source

BISPHOSPHONATE-RELATED OSTEONECROSIS OF THE JAW AND DENTAL IMPLANTS

open access: yes, 2016
Bisphosphonate (BP) is one of the possible riskfactors in the osteonecrosis of the jaw (ONJ). Surgical interventions during or after the course of treatment by using BPs may expose the patient under this risk. Animal studies, human studies, case reports,
ARISAN, Volkan   +3 more
core   +1 more source

Bisphosphonate-associated osteonecrosis can hide jaw metastases [PDF]

open access: yes, 2007
Background: Osteonecrosis of the jaw is a well known potential complication of bisphosphonate treatment but its pathogenesis is poorly understood. The current management of patients with bisphosphonate-associated osteonecrosis (BON) is based on “expert ...
M. Ragazzo   +9 more
core   +2 more sources

Bisphosphonates and Osteonecrosis of the Jaw [PDF]

open access: yes, 2009
Bisphosphonate-related Osteonecrosis of the Jaw (BRONJ) is a condition which, according to the American Association of Oral and Maxillofacial Surgeons (AAOMS), adversely affects between .8-12percent of the population, a small yet significant amount of ...
Leah Katz, Chaya
core   +1 more source

Engineered surface strategies to manage dental implant‐related infections

open access: yesPeriodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza   +7 more
wiley   +1 more source

Evaluation of medication-related osteonecrosis of the jaw using the Japanese Adverse Drug Event Report database

open access: yes, 2018
Ayaka Inada, Keiko Hosohata, Saki Oyama, Iku Niinomi, Yasuhiro Mori, Yuki Yamaguchi, Mayako Uchida, Kazunori Iwanaga Education and Research Center for Clinical Pharmacy, Osaka University of Pharmaceutical Sciences, Takatsuki, Osaka 569-1094, Japan ...
Uchida M   +7 more
core  

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