Results 91 to 100 of about 54,052 (278)

The association between osteopontin gene polymorphisms, osteopontin expression and sarcoidosis

open access: yesPLOS ONE, 2017
Sarcoidosis is a systemic inflammatory disease of unknown etiology. Osteopontin (SPP1, OPN) is an extra cellular matrix glycoprotein and cytokine with a known role in granuloma formation and in autoimmune and inflammatory diseases.To determine whether plasma OPN levels are elevated in patients with sarcoidosis and compare the frequency of four single ...
Hadas Lavi   +5 more
openaire   +4 more sources

Osteopontin-enriched formula feeding improves the T-cell-dependent humoral immune responses in infant rats

open access: yes, 2018
Previous studies have shown that osteopontin (OPN) can enhance infant resistance to infection. However, the underlying mechanisms remain to be explored.
Xiaoyan Chen (146508)   +5 more
core   +1 more source

Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer

open access: yesBMC Cancer, 2012
Background The metastasis-promoting protein S100A4 induces expression of ephrin-A1 and osteopontin in osteosarcoma cell lines. The aim of this study was to investigate S100A4-mediated stimulation of ephrin-A1 and osteopontin in non-small cell lung cancer
Rud Ane   +6 more
doaj   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Role of Osteopontin in Hypothyroid Anemic Woman and Their Association with Oxidative Stress

open access: yesInternational Journal of Integrated Health Sciences
Background: Hypothyroidism is frequently associated with anemia and oxidative stress, necessitating exploration of biomarkers like Osteopontin to better understand disease mechanisms.
Sumesh Prasad Sah   +5 more
doaj   +1 more source

Effect of Osteopontin on TIMP-1 Gene and Protein Expression by Fibroblasts

open access: yes, 2013
(A) Northern blot of 20 μg total cellular RNA per lane extracted from control and fibroblasts stimulated with 0.4 μg/ml and 1 μg/ml osteopontin. Both concentrations of osteopontin induced an increase of TIMP-1 expression. (B) The expression
José Cisneros (29358)   +10 more
core   +1 more source

Altered T cell immune profile and its prognostic implications in children with portal hypertension: A pilot study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Immune dysregulation in paediatric portal hypertension (PHT) is poorly understood. We aimed to characterise T cell phenotype and function and circulating immune mediators in children with PHT according to disease aetiology. Methods Forty‐four children with PHT (27 chronic liver disease [CLD]‐related and 17 portal vein thrombosis ...
Tengfei Si   +11 more
wiley   +1 more source

Representative photomicrograph of osteopontin immunostaining from diabetic rats.

open access: yes, 2013
Representative photomicrographs of osteopontin immunostained sections from control and diabetic rats treated with or without FT011. In control (A) and control treated with FT011 (B) rats, only few tubules were immunostained positively for osteopontin ...
Spencer J. Williams (180548)   +8 more
core   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

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