Results 91 to 100 of about 52,783 (282)

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer

BMC Cancer, 2012
Background The metastasis-promoting protein S100A4 induces expression of ephrin-A1 and osteopontin in osteosarcoma cell lines. The aim of this study was to investigate S100A4-mediated stimulation of ephrin-A1 and osteopontin in non-small cell lung cancer
Rud Ane, Lund-Iversen Marius, Berge Gisle, Brustugun Odd, Solberg Steinar K, Mælandsmo Gunhild M, Boye Kjetil   +6 more
doaj   +1 more source

Urinary Osteopontin Predicts Incident Chronic Kidney Disease, while Plasma Osteopontin Predicts Cardiovascular Death in Elderly Men

, 2017
<b><i>Background and Objectives:</i></b> The matricellular protein osteopontin is involved in the pathogenesis of both kidney and cardiovascular disease.
Feldreich, T,, Feldreich, T., Lind, Lars,, Helmersson, Johanna,, Carlsson, A. C., Risérus, Ulf,, Lars Lind, Johanna Helmersson-Karlqvist, Arnlov, J, Larsson, Anders,, Carlsson, AC, Risérus, U., Ärnlöv, Johan,, Anders Larsson, Tobias Feldreich, Axel C. Carlsson, Helmersson-Karlqvist, J., Carlsson, Axel C,, Helmersson-Karlqvist, J, Lind, L, Larsson, A, Feldreich, T, Larsson, A., Ulf Risérus, Riserus, U, Lind, L., Johan Ärnlöv   +26 more
core   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Role of Osteopontin in Hypothyroid Anemic Woman and Their Association with Oxidative Stress

International Journal of Integrated Health Sciences
Background: Hypothyroidism is frequently associated with anemia and oxidative stress, necessitating exploration of biomarkers like Osteopontin to better understand disease mechanisms.
Sumesh Prasad Sah, Sonu Sah, Sudeep Kumar, Manisha Arora, Dinesh Kumar, Raj Kumar   +5 more
doaj   +1 more source

Int J Parasitol [PDF]

Schistosomiasis is a major cause of fibrosis and portal hypertension. The reason 4-10% of infected subjects develops hepatosplenic schistosomiasis remains unclear.

core  

Osteopontin-driven partial epithelial-mesenchymal transition governs the development of middle ear cholesteatoma

Cholesteatoma is a common disease of the middle ear. Currently, surgical removal is the only treatment option and patients face a high risk of relapse. The molecular basis of cholesteatoma remains largely unknown.
Li Xie (108913), Aiguo Liu (129871), Xiang Lu (158823), Jin Hu (187088), Chao He (466651), Lingling Zeng (519902), Wen Zhou (49050)   +6 more
core   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Osteopontin Impairs Host Defense During Pneumococcal Pneumonia

, 2011
Methods. To determine the role of osteopontin in the host response during pneumococcal pneumonia, osteopontin knockout (KO) and normal wild-type (WT) mice were intranasally infected with viable S. pneumoniae. Results.
de Vos, Alex F., Tijmen J. Hommes, Arie J. Hoogendijk, Tom van der Poll, Schouten, Marcel, Alex F. de Vos, Hoogendijk, Arie J., Hommes, Tijmen J., Gerritje J. W. van der Windt, van der Poll, Tom, Florquin, Sandrine, Sandrine Florquin, van der Windt, Gerritje J. W., Marcel Schouten   +13 more
core   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source