Results 81 to 90 of about 52,783 (282)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Urinary osteopontin predicts incident chronic kidney disease, while plasma osteopontin predicts cardiovascular death in elderly men

, 2016
Background and objectives The matricellular protein osteopontin is involved in the pathogenesis of both kidney and cardiovascular disease. However, whether circulating and urinary osteopontin levels are associated with the risk of these diseases is less ...
Rudholm Feldreich, Tobias
core   +2 more sources

Relationship between serum osteopontin level and atrial fibrillation recurrence in patients undergoing cryoballoon catheter ablation

Türk Kardiyoloji Derneği Arşivi, 2017
Objective: Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with increased morbidity and mortality. Atrial fibrosis augments recurrence rate following AF catheter ablation.
Hacı Murat Güneş, Gamze Babur Güler, Ekrem Güler, Gültekin Günhan Demir, Filiz Kızılırmak Yılmaz, Mehmet Onur Omaygenç, Ayşe İstanbullu Tosun, Taylan Akgün, Bilal Boztosun, Fethi Kılıçarslan   +9 more
doaj   +1 more source

Az osteopontin gén polimorfizmusa egy román tarka tejelő tehenészetben

, 2014
A kísérlet célja az volt, hogy PCR-RFLP technika segítségével megvizsgáljuk, hogy egy román tarka tejelő tehenészet egyedei hordozzák-e az osteopontin gén polimorfizmusát, és eredményeinket összehasonlítsuk korábbi kísérletek eredményeivel.gjBiológiaBSc ...
Szappanos, Lilla Virág
core  

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway

Journal of Translational Medicine, 2012
Background Nasopharyngeal carcinoma (NPC) is well-known for its highly metastatic characteristics, but little is known of its molecular mechanisms. New biomarkers that predict clinical outcome, in particular the ability of the primary tumor to develop ...
Chen Chang-Han, Shiu Li-Yen, Su Li-Jen, Huang Chi-Ying F, Huang Shun-Chen, Huang Chao-Cheng, Yin Yu-Fang, Wang Wei-Sheng, Tsai Hsin-Ting, Fang Fu-Min, Chuang Wan-Chu, Kang Hong-Chang, Hwang Chung-Feng   +12 more
doaj   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

A multi-stage association study of plasma cytokines identifies osteopontin as a biomarker for acute coronary syndrome risk and severity

Scientific Reports, 2019
Cytokines play a critical role in the pathogenesis and development of cardiovascular diseases. However, data linking cytokines to risk and severity of acute coronary syndrome (ACS) are still limited.
Kuai Yu, Binyao Yang, Haijing Jiang, Jun Li, Kai Yan, Xuezhen Liu, Lue Zhou, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Xiaoting Luo, Wenhua Mei, Shunchang Sun, Liyun Zhang, Xiang Cheng, Meian He, Xiaomin Zhang, An Pan, Frank B. Hu, Tangchun Wu   +20 more
doaj   +1 more source

The association between osteopontin gene polymorphisms, osteopontin expression and sarcoidosis

PLOS ONE, 2017
Sarcoidosis is a systemic inflammatory disease of unknown etiology. Osteopontin (SPP1, OPN) is an extra cellular matrix glycoprotein and cytokine with a known role in granuloma formation and in autoimmune and inflammatory diseases.To determine whether plasma OPN levels are elevated in patients with sarcoidosis and compare the frequency of four single ...
Hadas Lavi, Miri Assayag, Assaf Schwartz, Nissim Arish, Zvi G Fridlender, Neville Berkman   +5 more
openaire   +4 more sources

Osteopontin presentation affects cell adhesion-Influence of underlying surface chemistry and nanopatterning of osteopontin

, 2010
Osteopontin is a promising coating material for biomaterials, being important both in remodeling and formation of mineralized tissue and in immunological responses.
Duch, M, Lovmand, J, Esben S. Sørensen, Jenny Malmström, Christensen, B, Sutherland, DS, Malmstrom Pendred, Jenny, Brian Christensen, Jette Lovmand, Mogens Duch, Duncan S. Sutherland, Sorensen, ES   +11 more
core   +1 more source