Results 181 to 190 of about 99,821 (371)
Small, EarlyView.This study introduces multifunctional, bioactive factor‐loaded porous microshuttles fabricated via a one‐step emulsification and chemical etching method. The poly(lactic‐co‐glycolic acid) microshuttles, featuring tunable pore sizes, enable loading and release of bioactive factors, and thereby enhance osteogenic marker expression and promote endothelial
Ke Song +5 more
wiley +1 more source
Relapsing-remitting multiple sclerosis: advances in disease-modifying therapies [PDF]
, 2015 Multiple sclerosis is a demyelinating disease affecting the central nervous system. It is the most prevalent disabling neurological condition among young adults, with onset typically between 20 and 40 years of age. Infiltrating immune cells and microglia
Kay, Kathleen Alexandra
core +1 more source
Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1 [PDF]
, 2008 Benjamin D. Hedley +8 more
openalex +1 more source
Small, EarlyView.We introduce a versatile 3D platform that recreates key physical and biological features of the human bone marrow. By integrating tunable silk biomaterials, stromal cells, and human hematopoietic progenitors, the model captures both healthy and diseased microenvironments, analysis of blood formation, and its disruption in pathological conditions ...
Christian A. Di Buduo +13 more
wiley +1 more source
Small Structures, EarlyView.Bone's complex hierarchical structure contains many internal interfaces, including the cement line (CL) around osteons. This article shows that the CL is stiffer and harder than surrounding bone but has different mineral–mechanics relationships. These findings challenge the view of the CL as a soft, protective interface and provide insights for ...
Astrid Cantamessa +11 more
wiley +1 more source
729: Osteopontin Levels in the Plasma of Patients with Transitional Cell Carcinoma of the Bladder may be Predictive of Recurrence and Survival [PDF]
, 2004 Celina Ang +6 more
openalex +1 more source
Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast
Australian Endodontic Journal, EarlyView.ABSTRACT Etidronic acid (HEBP) causes fewer alterations in dentine and can be used mixed with sodium hypochlorite during root canal preparation. This study investigated the cytotoxicity effects of the HEDP and EDTA on human periodontal ligament fibroblast cells. Primary culture was established from human periodontal ligament tissue of one donor and was
Bruno Vila Nova de Almeida +6 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source